Chemotherapy Types
This antimetabolite is used for solid tumors and sarcomas and works by stopping cell reproduction
Methotrexate
Bone marrow suppression affects these three blood components.
WBCs, platelets, and RBCs
Patients on Methotrexate should report these GI symptoms indicative of a bleed.
Coffee ground emesis and black tarry stool?
Methotrexate is contraindicated in this condition due to severe fetal risks.
Pregnancy
Methotrexate can be administered via these four routes.
PO, IV, IM, Intrathecal
This antitumor antibiotic binds to DNA, inhibiting its synthesis and repair.
Doxorubicin
Doxorubicin can cause this harmless but alarming discoloration of urine.
red discoloration
This intervention is crucial for Doxorubicin's IV administration to prevent tissue damage.
Monitor the IV site
Doxorubicin should not be given to patients with this severe hematologic condition.
myelosuppression
This is the only approved route of administration for Doxorubicin.
IV
This medication, used for leukemia and lymphoma, stops cell division during mitosis and is not bone marrow toxic.
Vincristine
A common side effect of Cyclophosphamide that requires increased fluid intake.
hemorrhagic cystitis
Patients receiving Cyclophosphamide should be encouraged to consume this amount of fluid daily.
2-3 liters
Vincristine should not be used concurrently with this therapy due to increased risks.
radiation therapy
Vincristine should always be infused using this device to prevent tissue damage.
Central Line
This alkylating agent is used for lymphoma, leukemia, and brain cancer, and kills rapidly growing cells.
Cyclophosphamide
This nerve injury side effect is common with Vincristine.
neuropathy
This should be administered prophylactically before chemotherapy.
An antiemetic
Topotecan should be avoided in patients receiving these types of vaccines.
Live virus vaccines
Cyclophosphamide is administered via these two routes.
PO, IV
This topoisomerase inhibitor is used for metastatic ovarian, cervical, and colorectal cancers and interrupts DNA synthesis.
Topotecan
This topoisomerase inhibitor can cause bone marrow suppression lasting up to 4-6 weeks post-infusion
Topotecan
To mitigate alopecia, patients on Vincristine should consider this option.
choosing a hairpiece
Cyclophosphamide can increase neuromuscular blockade when combined with this medication.
succinylcholine
Topotecan administration requires monitoring for this common GI side effect.
Diarrhea