MI Cancer Seek®
MI Cancer Seek® will reflex to this laboratory developed test when DNA content is < 50 ng.
What is MI Tumor Seek Hybrid?
Caris Assure sequences these two layers in the blood.
What are the plasma and buffy coat?
Per this company's website they "pioneered liquid biopsy in advanced cancer."
What is Guardant?
A first-in-class AI signature provided to assist clinicians with sequencing FOLFOX and FOLFIRI.
What is Caris FOLFIRSTai?
A physician has questions about a specific patient's final report and molecular results.
Who would you reach out to?
What is a MSL?
How many CDx indications does MI Cancer Seek® have?
What are 8 CDX indications?
This is the application for Caris Assure.
What is therapy selection?
This company offers a comprehensive testing selection that includes CDx based on WES/WTS as well as Additional Services like IHC and AI.
What is Caris?
Signature offered by Caris that may be used to classify CUP cases as well as provide insight into cases that are clinically ambiguous or have atypical presentation.
What is Caris GPSai?
Key Opinion Leader at large clinic will only use vendors integrated within EMR system. KOL expresses interest in integration. EMR system is Flatiron OncoEMR.
Who would you reach out to?
DNA, RNA, and AI Signatures are non-CDx sequencing features included with MI Cancer Seek and are listed as this.
What are Additional Services?
The assay utilizes circulating Nucleic Acid Sequencing (cNAS), a novel approach to liquid biopsy that analyzes cell-free DNA and RNA from plasma, plus genomic DNA and messenger RNA from circulating white blood cells (WBCs), to distinguish: (3 Answers)
What are somatic tumor variants, incidental CH, and incidental germline?
Name the IHCs included in Foundation Medicine's optional add on testing selection. (3 Answers)
What are PD-L1, FOLR1, and HER2?
A Caris program where a clinician is notified when a new therapy is approved for which they have a previously profiled patient that may be eligible.
What is the Look Back Program?
The Account Manager notices a trend of increased number of additional tissue requests and an increase in QNS/Limited tissue cases over the last 3 months with cases coming from a particular pathology department.
Who would you reach out to?
What is a PMID (Precision Medicine Initiatives Director)?
Name the biomarker for the pan-cancer CDx indication.
What is MSI-H?
Name the sensitivity and specificity of clinically actionable SNV and INDEL of Caris Assure.
What is 93.8% (sensitivity) and 99% (specificity)?
Tempus' CDX indications are for the following cancer type(s).
What is colorectal cancer?
A step the Caris lab performs to increase the proportion of tumor cells for testing and reduce non-cancer material diluting the tissue section prior to testing.
What is microdissection?
Your largest pathology department is refusing to release tissue on current inpatient due to "billing issues".
Who do you reach out to?
What is the AIM team (Account Implementation Manager)?
Name the 5 tumor types that have CDx indications not including pan-cancer.
What are breast, colorectal, melanoma, non-small cell lung, and endometrial cancer?
Name two reasons why tissue and blood results might be different.
What are tumor heterogeneity and shedding?
These two companies have an option to reflex to liquid biopsy if tissue CDx options QNS.
What is Tempus?
What is Foundation Medicine?
Motto displayed by Caris leadership by always asking, “What would I do if this patient was my mom?”
What is The Mom Rule?
Your largest account's EMR system went down for an extended amount of time. RN is unable to access reports for patients coming to clinic today. In addition, a new OP would like to place their first order, but staff at the office only knows how to order via EMR.
Who would you call? (3 answers)
What is:
POP team: to notify of downtime and to check with EMR team on ETA of issue correction
AM (Account Manager): to provide requisition in-service"
Customer Support: to email/fax final reports needed during downtime