Stimulants
Opioids
Caffeine & Common Stimulants
Stimulants and Withdrawals
Signs of Intoxication — From Opioids to Stimulants
100

This drug is known for producing a short, intense high followed by a crash, and was once a common ingredient in tonics and medicines of the 1800s.

What is cocaine?

100

This is the neurotransmitter that transmits pain. 

What is Substance P.

100

Snorting this drug delivers it to the brain in as little as 3 minutes, producing a short but intense high.

What is cocaine?

100

Sweating, watery eyes, runny nose, GI upset, cramping, restless leg syndrome, are all withdrawal symptoms of this substance.

What are opioids?

100

Euphoria, slowed breathing, pinpoint pupils, and drowsiness are classic signs of intoxication from this class of drugs.

What are opioids?

200

The feeling/sensation that there are “bugs" crawling around under or on the skin is caused by this substance.

What is methamphetamine?

200

Symptoms of withdrawal that are extended symptoms that can last for months after abstinence has begun.

What is protracted withdrawal? 

200

The smokable, “freebase” form of cocaine — popular in the 1980s — is commonly known by this street name.

What is crack?

200

Extreme fatigue, depression, and intense drug cravings are hallmark withdrawal symptoms from this stimulant.

What is methamphetamine?

200

Users of this stimulant often experience bursts of energy, increased heart rate, and talkativeness — followed by irritability as the high fades.

What is cocaine?

300

Stimulant that creates the strongest dependence?

Nicotine

300

This drug is 10 times stronger than morphine and was originally marketed as a “non-addictive” alternative.

What is heroin?

300

Withdrawal from this substance can cause headache, fatigue, anxiety, irritability, depressed mood, and difficulty concentrating.

What is caffeine?

300

This medication binds to opioid receptors without producing a full high, reducing cravings and withdrawal symptoms.

What is buprenorphine (Suboxone)?

300

Grinding teeth, dilated pupils, restlessness, and hallucinations that feel like “bugs under the skin” are linked to intoxication from this powerful stimulant.

What is methamphetamine?

400

Chronic use of these drugs weakens blood vessels and increases the risk of stroke.

What are stimulants?

400

This medication is often called the “heroin antidote” because it blocks opioids from attaching to receptors in the brain.

What is naloxone (Narcan)?

400

DAILY Double:

All three of these stimulants — caffeine, cocaine, and methamphetamine — increase alertness and energy by affecting this same neurotransmitter system, but differ drastically in speed, strength, and duration of effect.

What is the dopamine system (or the central nervous system’s dopamine pathway)?

400

A pregnant woman struggling with heroin use begins a supervised medication program that prevents withdrawal and stabilizes the fetus. This evidence-based approach is known as what?

What is medication-assisted treatment (MAT)?

400

This stimulant can cause jitteriness, restlessness, and even panic attacks when consumed in high doses.

What is caffeine?

500

The use of this stimulant triggers a dopamine release so powerful it exceeds any naturally occurring reward the brain can produce.

What is methamphetamine?

500

Combining opioids with other depressant drugs greatly increases the risk of this fatal condition.
 

What is respiratory failure (or overdose)?

500

This stimulant is associated with the following medical uses: bronchodilator for asthma patients, treatment of headaches because it constricts blood vessels in the brain; counteracts any drops in blood pressure when using pain medications.

What if caffeine?

500

While there are FDA-approved medications to treat opioid dependence, there are currently no approved MAT options for this category of drugs — making behavioral therapies the main treatment approach.

What are stimulants (such as methamphetamine or cocaine)?

500

Daily Double:

Elevated heart rate, increased blood pressure, and heightened alertness are early signs of intoxication from this legal, yet highly addictive, stimulant.

What is nicotine?