Defining the Disease
A Dark History of Treatment
Neurobiology & Dopamine
Diagnostic Evolution (DSM)
Social & Family Impact
100

NIDA defines this as a chronic, relapsing brain disease characterized by compulsive seeking despite harmful conseqNIDA defines this as a chronic, relapsing brain disease characterized by compulsive seeking despite harmful consequences.uences.

What is Addiction?

100

Introduced in 1879, this "cure" involved injecting solutions containing gold, strychnine, and alcohol.

What is the Keeley Cure (Gold Cure)?

100

This primary chemical messenger is responsible for the "surge" of pleasure the brain remembers and wants to repeat.

What is Dopamine?

100

The DSM-5 removed separate categories for Abuse and Dependence in favor of this single umbrella term.

What is Substance Use Disorder (SUD)?

100

Infants born to opioid-dependent mothers are at high risk for this specific syndrome.

What is Neonatal Abstinence Syndrome?

200

ASAM states addiction is a primary, chronic disease involving these four brain circuits: reward, motivation, memory, and this.

What is spiritual manifestations?

200

In the early 1900s, this therapy put individuals into a drug-induced coma to wake up "cured," often resulting in high death rates.

What is Bromide-sleep therapy?

200

These "communication centers" in the brain number in the billions and pass messages back and forth.

What are Neurons?

200

This clinical criterion, defined as a strong desire or urge to use, was officially added in the DSM-5.

What is Craving?

200

This term describes the financial strain on families caused by substance purchases or job loss.

What is Economic Burden?

300

ASAM states addiction is a primary, chronic disease involving these four brain circuits: reward, motivation, memory, and this.

What is self-control?

300

This 1935 federal law mandated the creation of "Narcotics Farms" in Kentucky and Texas.

What is the Porter Act?

300

This imaging technology uses colored scans to show that addicted individuals have lower levels of Dopamine D2 receptors.

What is a PET scan?

300

This specific diagnostic criterion was removed in the DSM-5 because it was applied inconsistently across different populations.

What is Recurrent substance-related legal problems?

300

This concept involves a community's conceptual system of beliefs, norms, and values that influence how people view the world.

What is Culture?

400

This specific brain region is responsible for judgment and impulse control, and its impairment leads to "Executive Dysfunction."

What is the Prefrontal Cortex?

400

Between 1948 and 1952, this surgical procedure was used to treat addiction by removing a specific lobe of the brain.

What is a Frontal Lobotomy?

400

In the reward pathway, this specific brain structure shows up as red/yellow in controls but less intense in addicted brains.

What is the Striatum?

400

According to the DSM-5 severity grading, a "Severe" diagnosis is determined by meeting this many symptoms.

What is 6 or more?

400

In the "Cultural Iceberg," these three elements (Values, Beliefs, and Norms) are found in this section.

What is "Difficult to See"?

500

This term describes the brain's ability to continuously remodel its organization to optimize neural networks.

What is Neuroplasticity?

500

In the 1930s-1950s, the Colorado State Penitentiary used this bizarre method involving abdominal blisters and re-injection.

What is the re-injection of drained blister fluids?

500

This brain region, the "3lbs of gray and white matter," coordinates everything we feel, think, and do.

What is the Brain?

500

This web-based tool is used in New York for initial and concurrent level-of-care determinations.

What is LOCADTR?

500

This intervention strategy aims to help family members engage in recovery for this specific reason.

What is to meet their own needs?