Registry Program
AIRCF1, 2, & 3
What are the clinical trials for Cayston approval?
Provides a quantitative measure of the patient's experience with overall health, including respiratory symptoms.
What is the CFQ-R?
22 vs 11
What are the serious adverse events for Cayston-treated vs TNS-treated groups?
45.1%
What is the Pa prevalence for patients on a CFTR modulator?
Square Dance
What is the Colorado State Dance
was an open-label follow-on trial tat assessed the safety and microbiology profile of Cayston
What is AIRCF-3?
Graphic Illustration of respiratory symptoms assessed in all patients across disease severity.
What is a forest plot?
All patients were treated with Cayston
What is the Extension phase of the Active Comparator?
A phenotypic variant associated with Pa, may be considered difficult to eradicate and is associated with an abrupt change in lung function.
What is Mucoid Pa?
Gold and Silver
What are 2 things that are mined in Colorado?
Evaluated BID vs. TID
What is AIR-CF2?
10.5% & 10.4%
What is the improvement in FEV1 across adult and pediatric patients on day 28 of treatment?
7.4% above baseline
What is the treatment effect after 6 courses of Cayston Therapy?
The slope of this curve remains consistent albeit delayed.
What is the lung function FEV1 percent predicted vs age by birth cohort?
Skiing
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Evaluated Cayston in the setting of eradication?
What is the ALPINE study?
Dysgeusia
What is altered taste? A low incidence was reported in both treatment groups.
2.7%, Statistical Superiority Reached
What is the adjusted mean actual change in FEV1% across 3 Treatment Cycles?
Lung function has improved over time but is still short of the CFF goals for FEV1.
What is the median FEV1 percent predicted in 1998 and 2018?
Colorado Amendment 64, 2012
what is the year and amendment that legalized recreational marijuana?
Phase IV trial completed to satisfy the EU regulatory body and provide comparative data.
What is the active comparator trial?
3% Incidence Rate
What is Bronchospasm? A complication associated with nebulized therapies.
CFQ-R
What is a patient reported outcome tool that is not validated by the FDA?
The majority of adults with CF are leading active lives as working professionals or students.
What is the CF population breakdown by employment status?
Denver
What is the Colorado state capital?