Neoplasia terminology (nomenclature)
Describes the cell/tissue of origin
What is a prefix?
Malignant tumour of squamous cells
What is squamous cell carcinoma?
A measurement of melanoma tumor thickness
What is breslow depth?
ABCDE (what do they stand for?)
What is acronym Asymetry, Border, Colour, Diameter and Evolution?
Most common skin cancer
What is BCC?
Benign neoplasm
What is a suffix - oma
Malignant tumour of basal keratinocytes
What is basal cell carcinoma ?
1-2mm
What is stage II breslow depth?
Common environmental risk factor of malignant melanoma
What is UV radiation?
Clusters of mutated cells protruding dermo/epidermal junction
What is BBC characteristics?
Degree of differentiation
What is a grading term?
Neuroendocrine (Merkel cell) tumour - malignant
What is a merkel cell carcinoma?
Confined to epidermis (in situ)
What is clark level I?
Phases of melanoma progression
What is radial and vertical growth phase?
Local destruction of skin and surrounding tissue if left untreated
What is a rodent ulcer?
Premalignant epithelial changes
What is dysplasia?
Malignant melanocyte origin
What is melanoma?
Invasion into subcut tissue
What is Clark level V?
What is radial growth phase? (first phase of progression)
Main dermal characteristics in diagnosis
What is papule or nodule?
Premalignant cells that have not invaded
What is “in situ”?
Endothelial cells (blood/lymphatic vessels) origin - malignant
What is an angiosarcoma ?
Filling of papillary dermis
What is Clark level III?
Invasion into the dermis and beyond (risk of metastasis increases)
What is vertical growth phase? (Second phase of progression)
Grows slowly over months to years
What is course of progression?