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Urine Trouble!
Remember when blood letting and whiskey were cool?
100

The combination of these two antibodies gives the greatest specificity for the diagnosis of rheumatoid arthritis.

Anti-cyclic citrullinated peptide antibody and rheumatoid factor.

100

What is the treatment of choice for diabetes in pregnancy?

Insulin.

100

What is the recommended door to balloon time by ACC/AHA for ACS?

90 minutes

100

Name the formula used to determine if AKI is pre-renal or post-renal.

FeNa.

100

The invention of what in 1666 allowed doctors see disease-causing organisms?

Microscope.

200

In patients with gout who require urate-lowering therapy, what is a viable alternative for those who have an adverse reaction to allopurinol?

Febuxostat.

200

What class of diabetic drugs promote the highest weight loss?

GLP-1 receptor agonists.

200

What is a genetic cause of sudden cardiac death with RBBB and ST elevation in V1-V3?

Brugada syndrome.

200

What is the approximate 5 year survival rate of a patient who begins hemodialysis today (assuming no other competing illness)?

35%

200

What percentage of the population was killed in Europe and Asia because of the Bubonic Plague?

75%.

300

What three characteristics are pathognomonic for Felty syndrome?

Rheumatoid arthritis, neutropenia, and splenomegaly.

300

What class of diabetes drugs have an FDA warning for causing euglycemic ketoacidosis?

SGLT-2 inhibitors

300

Taking lithium during the first trimester of pregnancy can result in this cardiac abnormality.

Ebstein anomaly.
300

What agents are recommended to prevent contrast-induced nephropathy?

Hydration and supportive care (no drugs recommended).

300

How many body humors did the Romans believe had to be balanced?

Four. Black bile, yellow bile, phlegm, and blood.

400

Name the four major seronegative spondyloarthropathies.

Psoriatic arthritis, ankylosing spondylitis, inflammatory bowel disease, and reactive arthritis.

400
What class of oral diabetic drugs have an FDA indication for reduction of the risk of major cardiovascular events in DM2?

SGLT-2 inhibitors

400

What are the two high-intensity statins and their dosages?

Atorvastatin 40-80mg and rosuvastatin 20-40mg.

400

What drug has been shown to slow down decline in autosomal dominant polycystic kidney disease (ADPKD)?

Tolvaptan.

400

Who was the glass-blower/physicist who invented the thermometer?

Gabriel Fahrenheit.

500

Name 6 antibodies associated with SLE. What is the most sensitive and what is the most specific?

ANA (most sensitive), anti-Sm (most specific), anti-dsDNA, lupus anticoagulant, anticardiolipin IgM/IgG, anti-beta2-glycoprotein1, anti-Ro/SSA, anti-La/SSB, anti-U1 RNP.

500

Name the landmark trial in 2009 that showed intensive glucose control increased mortality in ICU patients.

NICE-SUGAR trial.

500

What are the 5 components that make up the HEART score?

History, EKG, age, risk factors, initial troponin.

500

What is the imaging modality of choice for asymptomatic microhematuria workup?

CT urography.

500

In 1796, who developed the first vaccination to prevent the spread of small pox?

Edward Jenner.