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Cell Cycle
DNA
Mitosis
Cell Cycle Regulation
Cancer
100

The 2 main phases of the cell cycle

Interphase and Mitosis

100
The structures that hold together sister chromatids are ________________________.
centromeres
100

During what phase does all of the following occur? Tighter coiling of chromosomes (condensing), breaking down of the nuclear envelope, disappearing of nucleolus.

Prophase

100

Stopping points within the cell cycle that regulate the health and progress of a cell

checkpoint

100

What does a mutation in proto - oncogene do?

Causes oncogene to increase cell division

200

What macromolecules are responsible for monitoring a cell's progress from phase to phase during the cell cycle (at each checkpoint)?

Proteins

200

Phase when DNA is replicated

S phase

200
The process by which nuclear material is divided equally between two new cells is ______________.
Mitosis
200

The uncontrolled division of cells is known as __________.

Cancer

200

What tumor suppressor protein stops cell cycle progression to repair damaged DNA

p53

300
The longest phase of the cell cycle.
Interphase
300
The identical two halves of a doubled chromosome structure are called _________________.
sister chromatids
300
The phase of mitosis in which chromatids separate from each other is ___________________
anaphase.
300

This regulator starts the cell cycle

proto-oncogene

300

Are proto - oncogene mutations dominant alleles or recessive allele trait?

Dominant Aa or AA

400
______ is a substage of interphase when the cell is growing, protein production is high, and the cell is preparing to replicate the DNA.
G1
400

If looking at a cell underneath a microscope and the DNA is visible, is the cell in interphase or mitosis?

It is in mitosis

400
Chromosomes line up at the equator during ____________.
metaphase
400

Programmed cell death

Apoptosis

400

Are tumor suppressor genes mutations dominant alleles or recessive allele trait?

Recessive - so aa only

500

Checkpoints throughout the cell cycle are regulated by _______________.

cell cycle regulators

500

Long strands of DNA inside the nucleus (like cotton candy).

chromatin

500

Name the phases of MITOSIS in the correct order.

Prophase, Metaphase, Anaphase, Telophase, Cytokinesis

500

This regulator stops tumors from forming

tumor suppressor gene

500

What does a mutation to the tumor suppressor do?

STOPS the tumor suppressor gene from doing its job - so it increases cell division