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Cell Cycle
DNA
Mitosis
Cell cycle regulation
Cancer
100

The 5 phases of the cell cycle (in order)

G1, S, G2, M phase (mitosis), cytokinesis

100
The structures that hold together sister chromatids are ________________________.
centromeres
100
During what phase does all of the following occur? Tighter coiling of chromosomes, breaking down of the nuclear envelope, disappearing of nucleolus.
Prophase
100

Stopping points within the cell cycle that regulate the health and progress of a cell

checkpoint

100
Overactive positive regulators are called __________.

oncogenes

200
What life substances are responsible for monitoring a cell's progress from phase to phase during the cell cycle?
Enzymes or proteins
200

Phase when DNA is replicated

S phase

200
The process by which nuclear material is divided equally between two new cells is ______________.
Mitosis
200

The uncontrolled division of cells is known as __________.

Cancer

200
Cancer cells can reproduce rapidly because they spend less time in _____________.
interphase
300
The longest phase of the cell cycle.
Interphase
300
The identical two halves of a doubled chromosome structure are called _________________.
sister chromatids
300
The phase of mitosis in which chromatids separate from each other is ___________________
anaphase.
300

_______ is a an important cell cycle regulator. It must pair with _______, a family of enzymes, and together they push the cell cycle forward.

Cyclin; CDK

300

Cancerous cells are able to bypass the many layers of protection and regulation. For that reason, cancer is considered a _______________ ________.

multistep process

400
______ is a substage of interphase when the cell is growing, protein production is high, and the cell is preparing to replicate the DNA.
G1
400

If looking at a cell underneath a microscope and the DNA is visible, what does this say about the condition or state of the cell?

It is in mitosis

400
Chromosomes line up at the equator during ____________.
metaphase
400

Programmed cell death

Apoptosis

400

This tumor suppressor is most active in the G1-S transition and the G2-M transition. It is responsible for stopping a cell when DNA damage is detected

p53

500

Checkpoints throughout the cell cycle are regulated by _______________.

enzymes

500
Long strands of DNA inside the nucleus.
chromatin
500
Name the phases of MITOSIS in the correct order.
Prophase, Metaphase, Anaphase, Telophase
500

Name the 3 checkpoints within the cell cycle.

1. At the G1-S transition

2. G2 phase

3. M phase, during the metaphase - anaphase transition