Molecules
Signal Integration
Neural Crest
RTKs
Cell Replication
100

The types of molecules that can act as extracellular signals.

What are Lipids, Proteins, or Ions?

100

The name for the process of conversion of information (via molecules) from an external signal.

What is signal transduction?

100

The name for the transition that allows a neural crest cell begins to migrate.

What is EMT (Epithelial to Mesenchymal Transition)?

100

The molecule that preforms the signal transduction step (first contact with ligand).

What is receptor protein

100

The cell phase in which DNA is replicated.

What is S phase?

200

The name for close proximity signaling around a cell.

What is Paracrine signaling?

200

The name for enzymes add a phosphate group to their substrate.

What are kinases?
200

The ligand found in-between digits that opposes Shh signaling activity.

What is BMP signaling?

200

The enzyme that turns off activated RTKs at a specific amino acid.

What are tyrosine phosphatases?

200

The name for programmed cell death.

What is apoptosis?

300

The name for small intracellular signaling molecules

What are secondary messengers?

300

The cell response that takes the longest time of all.

What is a change in gene expression?

300

The developmental layer that the neural crest arises from.

What is the Ectoderm?

300

The name of the energy source used to switch on G proteins.

What is bound GTP?

300

The proteins that facilitate the tight "twisting" of DNA around histones

What is chromatin remodeling factors?

400

The name of a category of extracellular signal that stimulates cell division.

What is mitogens?
400

The process of converting DNA data into protein, taking place in the nucleus.

What is Transcription?

400

Examples of derivates from the neural crest cells.

What are Melanocytes (pigment cells), Neurons of the PNS, Facial Bones?

400

The broad function of RTKs as a whole.

What is Growth Factors?

400

The actions of cyclins in the cell cycle.

What are Propelling the cycle forward, Regulating cell expression by stage, and binding to CDKs?

500

The way that large, hydrophilic, foreign substances (nicotine, morphone, menthol, etc.) exert their effects on the cellular level.

What is cell-surface receptors?

500

The biggest reason that all human cells are not morphologically identical (look/act different).

What is Gene transcription

500

The term used to describe when multiple regulatory pathways interact to control gene expression.

What is Combinatorial Control?

500

The category of mutations that leads to uncontrolled cell growth (tumours) due to a single loss in protein function.

What is loss of phosphatases?

500

The order of cell cycle that leads to cell division, including the "committed step".

What is G1 -> S -> G2 -> M -> C, G1 as the committed step.