Ligands
Receptors
Second messengers
Signaling
100

This ligand is produced by fat cells and downregulates appetite while upregulating metabolic rate

What is leptin

100

These receptors are dimerized by ligand binding

What are RTKs?

100

the enzyme that can convert ATP into cAMP

What is adenylyl cyclase?

100

A local signal not involving the blood system

What is paracrine

200

This ligand is an autocrine negative regulator of muscle growth

what is myostatin?

200

These receptors can bind to DNA

What is a nuclear receptor?

200

An ATP derivative used as a signaling molecule

what is cyclic AMP?

200

a hormonal signaling involving the blood system

What is endocrine?

300

The gene promoter activated by leptin and erythropoietin

What is a cytokine response element?

300

Activation of this receptor increases cAMP levels

What is dopamine receptor 1 / GPCR?

300

The only ion known to be a 2nd messenger

What is calcium?

300

A secreted signal detected by the same cell or type of cell.

What is autocrine?

400

This ligand is the end product of a synthesis pathway that starts with Tyrosine as a precursor.

What is dopamine?

400

An intracellular receptor that senses amino acid levels

What is mTOR?

400

Dopamine receptor 2 signaling lowers the amount of this second messenger

what is cyclic AMP?

400

The type of signaling used to neurons to communicate with one another

What is synaptic?

500

This ligand is a positive regulator of muscle growth

Insulin-like growth factor 1

500

A signal where both ligand and receptor are transmembrane or membrane anchored proteins

What is cell-attached signaling?