Reception, Transduction, Response
What are the 3 stages.
This is the main way that cells bind and respond. This receptor is made of Alpha and Beta chains.
What is an Integrin or CAM
Often linked to taste and olfactory responses.
What are G-Linked Receptors.
This is when a signal molecule attaches to a special protein, beginning a reaction.
What is Reception.
It is made of seven transmembrane alpha helices that are non catalytic receptors.
GPCR
This specific type of receptor does not reside on the plasma membrane; instead, it binds to small, nonpolar ligands like testosterone or estrogen and travels directly into the nucleus to act as a transcription factor
What is an Intracellular Receptor (or Steroid Hormone Receptor)
This is an enzyme catalyzing transfer of a phosphate group.
What is a Kinase.
Signal ligands to bind to two receptor polypeptides, Activates the interior tyrosine kinases by adding phosphates, activates relay proteins. What do we call the coupling of tyrosine kinases?
Dimers/Dimerization
Unlike G-protein coupled receptors, this class of membrane receptors must undergo dimerization and autophosphorylation of their intracellular domains before they can activate multiple different relay proteins simultaneously