Structure
Determines protein Structure
What is Amino acid sequence
Interactions that hold the substrate to the active site
What is noncovalent bonding
Number of phases in mitosis
What is 6
Utilization of aerobic fermentation
What is the Warburg Effect
High concentration of solute in solution
What is hypertonic solution
Ways that phosphorylation changes proteins function
Activated by a small nonpolar signaling molecule
What is intracellular receptor
The structure that pulls and degrades the microtubules
What is kinetochore
Utilized by cancer cells to metastasize
What is proteases
Source of new muscle cells
What is fibroblasts
Signs a cell is in apoptosis
What are blebs and nuclear collapse
Ways that signaling leads to cellular responses
What is changing existing protein function and altering gene expression
Composition of contractile ring
Two ways that cause hyper-proliferation
What is mutated oncongenes and tumor suppressor genes
Professor Cohen’s ID major
What is history
Epithelial cell orientation
What is apical surface on the lumen side and basal lateral surface attached to basal membrane
Off signal for phosphorylated proteins
What is protein phosphatase
Pausing mechanism of mitosis
What is p27 sequestering
Secretion of signals that lead to growth of blood vessels
Molecule binds to a protein and prevents the binding of another molecule at a different location
What is non competitive inhibition
Barrier that prevents fluid and other substrates from moving between membranes
What is tight junction
The signaling pathway that results in mitosis
What is :
RTK activates Ras GEF -> activates Ras protein -> activates MAP3K -> phosphorylation cascade
MAPK activates Cdc25 phosphatase ->dephosphorylates M-Cdk ->positive feedback on Cdc25
Signaling pathway that allows for S phase
What is mitopen -> mitogen receptor -> activated G/A-Cdk -> phosphorylation of Rb protein -> Rb protein leaves DNA strand -> gene transcription for entry into S phase
The diabolical superpowers of cancer
What is
1. Growth even in absence of normal “go“ signals
2. Growth despite “stop” commands
3. Evasion of built-in autodestruct mechanisms
4. Ability to stimulate blood vessel construction
5. Effective immortality
6. Power to invade other tissues and spread to other organs
Vitamin that is used to synthesize FADH2
Riboflavin