DiaBasics
What are 3 types of diabetes that can require insulin?
Type 1, Type 2, Gestational
What are the 2 main types of insulin?
Long-acting and short-acting insulin
What is the primary objective of the Bergenstal RCT comparing CeQur's bolus patch to an insulin pen?
Non-inferiority of patch compared to pen in lowering A1C
CeQur Simplicity is indicated for use in persons over the age of
21
How many alcohol prep pads/wipes should be used to clean the skin?
2
These are the two complementary hormones that regulate blood sugar levels in normal glucose metabolism
Insulin and Glucagon
When does the peak effect of short-acting insulin occur?
2 to 3 hours after injection
What was the primary endpoint in the Bergenstal RCT?
Change in A1C from baseline compared to insulin pens to Week 24
What concentrated insulin is indicated for use in CeQur Simplicity?
NONE!
After the patch is primed and any additional large are bubbles are removed from the reservoir, how many more times should the patch be clicked?
4 times
Name two other drug classes that the ADA Guidelines suggest before insulin in management of hyperglycemia in T2D
SGLT2 Inhibitors and GLP1 RAs
According to clinical studies, what percentage of patients do not take insulin outside of the home?
72%
Results from Bergenstal's (2019) sub-analysis with continuous glucose monitoring, patients increased Time in Range by
50% after 24 weeks
How many injections does a single 4-Day CeQur Simplicity patch replace?
12
What does it mean when the tan insulin delivery buttons on the patch "lock out"?
The patch is out of insulin or the cannula is compromised, therefore, the patient needs to remove the patch
Time in Range defines clinical target for TIR percentage of greater or equal to (evidenced to be equivalent to an A1C of <7%)?
70%
How many missed mealtime doses of insulin can raise your A1C by almost 1% per week?
4
According to the human factors study, Zraick et al, ADA Poster (2016), how many times did it take most patients to feel comfortable applying the patch?
1-3 times
What types of insulin were included in our studies and therefore are indicated for use in CeQur Simplicity?
Humalog U100 and Novolog U100
If a patient asks how long the cannula is, what do you tell them?
6mm
This concept or nickname describes the eight key contributors to hyperglycemia in T2D
What are the two different ultra-rapid-acting insulins on the market?
Fiasp and Lyumjev
How did the patch compare with the pen in terms of hypoglycemia and adverse events in the Bergenstal RCT (2019)?
Both groups had similar rates of hypoglycemia and adverse events
What is CeQur Simplicity's indication?
The CeQur Simplicity On-Demand Insulin Delivery System is intended for subcutaneous, bolus delivery of insulin for the management of diabetes mellitus in adult persons requiring insulin
If an HCP insists that a patient use concentrated insulin in the patch, we need to ask the HCP for what before we start the training?
Dosing in CLICKS, instead of units