Blood & Guts
Anatomy makes me nervous
Hook-ups
Can you give me directions?
Out & About
100
Supplies ICP, inferior half of cerebellum & inferior half of vermis. Is a branch of what?
What is PICA, a branch of the vertebral artery
100
Separates the anterior lobe from the posterior lobe Separates the posterior lobe from the flocculonodular lobe
What is primary fissure What is the posteriolateral fissure
100
These originate from the inferior olive and project via ICP to the _____ (side) cerebellum. They make excitatory synapses with these two cell types.
What is climbing fibers. These originate from the inferior olive and project via ICP to the contralateral cerebellum. They make excitatory synapses with purkinje cells and deep cerebellar neurons.
100
The turn by turn directions for the corticopontine input to the medial zone
Occipital lobe & medial cortex (trunk area) --> Ipsilateral pontine nuclei --> Dessucate as transverse pontine fibers --> Enter MCP--> Terminate as mossy fibers
100
The LVST is made up of axons of these neurons. And the tracts function is to facilitate anti-gravity extensor muscles
What is lateral vestibular nucleus
200
Supplies the deep cerebellar nuclei & what else?
What is SCA, also the SCP & superior half of cerebellar cortex
200
This is the oldest cerebellar region and it is primary involved in these two functions
What is the flocculonodular lobe: balance & eye movement
200
Involved in informing the cerebellum about planned & ongoing movement, mossy fibers directly excite __*__s & deep cerebellar nuclei. __*__s inturn excite ALL cells with synapses in the _____ layer via their parallel fibers that run PARALLEL to the folia.
What are granular cells What is the molecular layer (stellate cells, purkinje dendrites, basket cells)
200
Three "roads" I can take to enter ipsilaterally through the ICP to the medial zone
What are: dorsospinalcerebellar tract Cuneocerebellar tract Trigeminocerebellar tract
200
These are the fastigial nucleus's two projections
What is the VL thalamus & Medullary Reticular Formation
300
Supplies a strip of ventral cerebellum including the flocculi; it also supplies ____ and is a branch of _____.
What is AICA. MCP. Basilar artery.
300
Names of internal nuclei from medial to lateral & mnemonic for remembering
What is Fat (Fastigial) Guys (globose) Eat (Emboliform) Donuts (Dentate)
300
These cells are: * The only cells projecting OUT of the cerebellar cortex * Involved in timing of events or act as triggers for behavior * They also have complex sodium/calcium spikes that together with a slow discharge rate help develop motor memory via LTD.
What are purkinje cells.
300
I'm in the spinal cord following the "spy"...where will she lead me?
Across the ventral white commissure to ventral spinal cerebellar tract Up to and across SCP to enter the cerebellum
300
A lesion here produces hypertonicity (bragging rights for explaining why)
What is ICP 1. interrupts inhibition on lateral vestibular neurons (therefore promoting extension) 2. Interrupts excitation on medullary reticular formation (MRST) which usually inhibits extensors
400
These three axon types make up the white matter & respectively are entering and leaving
What is purkinje axons leaving & mossy fibers & climbing fibers entering
400
The three layers of the cerebellar cortex from superficial to deep & which cell nuclei are found in each layer & which are inhibitory/excitatory
What is: Molecular: Basket, Stellate Purkinje: Purkinje Granular: Granular (only excitatory, all others inhibitory) & golgi
400
Damage to this cerebellar blood supply and it's associated peduncle will result in hypertonia
What is PICA/ICP = hypertonia
400
I don't feel dizzy anymore, thanks for the directions!
Vestibular apparatus nuclei --> To medial cerebellum ipsilaterally via ICP
400
You just showed an example of testing for dysmetria & disdiodochokinesia! And yes, that is the location of a lesion that would result in these symptoms.
Dysmetria: pt touches nose to your finger (looking for overshoot) disdiodochokinesia: inability to perform rapid alternating movements What is SCP, paravermis or lateral hemisphere
500
Number of synapses one purkinje cell can make
What is 40,000
500
The cerebellum is derived from this structure
What are: The alar plates of the mesencephalon
500
Purkinje fibers from the flocculonodular lobe synapse here
What are vestibular neurons (& fastigial neurons)
500
Thanks for the directions! This information for timing & motor learning was really important to deliver!
Inferior olivary nucleus of medulla --> Dessucate in contralateral cerebellum via ICP
500
It connects vestibular nuclei to occulomotor nuclei and is involved with eye movements
What is MLF (medial longitudinal fasiculus)