LINES OF DEFENSE
MECHANICAL & CHEMICAL DEFENSES
PHAGOCYTOSIS
INFLAMMATION & FEVER
COMPLEMENT & INTERFERONS
100

Fever, inflammation, and phagocytes belong to this line of defense

What is the second line of defense?

100

This mechanical defense provides less protection than the skin

What are mucous mebranes?

100

These white blood cells predominate early in infection

What are neutrophils?

100

Redness, heat, swelling, and pain are classic signs of this process

What is inflammation?

100

This complement pathway is activated by antibodies binding to foreign cells

What is the classical pathway?

200

Skin and mucous membranes make up this line of defense

What is the first line of defense?

200

This oily secretion from sebaceous glands inhibits growth of certain bacteria and fungi

What is sebum?

200

The chemical attraction of phagocytes to an infection site is called this

What is chemotaxis?

200

Increased diameter of blood vessels during inflammation is called this

What is vasodilation?

200

This complement pathway is activated directly by microbial polysaccharides

What is the alternative pathway?

300

Defenses that protect against all pathogens are called this

What is nonspecific resistance?

300

These structures move mucus upward toward the throat in the respiratory tract

What is the ciliary escalator (or cilia)?

300

This structure forms when a phagosome fuses with a lysosome

What is a phagolysosome?

300
The part of the brain that changes the body's thermostat

What is the hypothalmus?

300

Both complement pathways trigger cleavage of this protein

What is C3?

400

B cells producing antibodies makes up this line of defense

What is the third line of defense?

400

These proteins limit the available iron for bacteria

What are transferrins?

400

This process coats microbes to improve phagocyte attachment

What is opsonization?

400

The process that allows phagocytic cells to squeeze through endothelial cells

What is emigration?
400

These cause cells to produce antiviral proteins

What are interferons alpha and beta?

500

The immune system's ability to fight a particular pathogen

What is specific resistance?

500

This enzyme found in tears, saliva, and nasal secretions breaks down Gram-positive cell walls

What is lysozyme?

500

This bacterial cell structure can prevent the adeherence stage

What is a capsule?

500

Damaged cells release these chemicals to trigger inflammation

What are histamine, prostaglandins, and kinins?

500

Proteins C3a and C5a cause this immune response

What is inflammation?