Model Organisms
Scientists use THIS MODEL ORGANISM to identify diseases genes and test gene therapy and drug based therapeutic approaches to check their effectiveness and safety in preclinical studies before using them for clinical trials.
A mouse
________ are typically proteins produce by diseased tissue or proteins whose production is increased when a tissue is diseased.
Biomarkers
Test useful for patients whose medical and family histories suggest a genetic cause for their signs and symptoms.
What is whole-genome sequences (WGS)? or Whole-exome sequencing (WES)?
__________ detect disease earlier, enduring a more accurate, beneficial and cost-effective outcome to disease
medical diagnostic tests
Monitor blood pressure, blood oxygen levels and hormone concentrations
Nanodevices
This gene is found in mice and human. It codes for the protein leptin a hormone found in adipose tissue released to help the body maintain normal weight longterm
What is Ob gene ?
Circulating tumor DNA (ctDNA) are released where when tumor cells die ?
Into the bloodstream
Isolate genomic DNA from a single cell that is then subjected to PCR to produce sufficient DNA to be sequenced
Single-cell sequencing
Therapeutic proteins can be produced by
Bacteria, Animals, Plants
Can unclog arteries, detect and eliminate cancer cells; smart drug that could seek out and target specific cells
What are Nanoparticles ?
Scientists want to identify __________ model organisms can lead to the formation of hypotheses and predications about how these genes may function in human.
What are key genes ?
Prenatal cell-free DNA (cfDNA) screens for?
Genetic disorders
Powerful tool for analysis of genes expressed by cells within a population, allowing researchers to differentiate genetic variations among cells
RNA sequencing (RNA seq)
Genes involved in the growth of cancer cells
oncogenes
Tiny particles that can be filled with drugs; made from materials that closely resembles lipids found in cell membranes
Microspheres
If the Ob gene is _________ and leptin is not produced mice and humans become __________
What is nonfunctional and obese ?
Breast cancer CA125 is what type of test ?
Blood Test
What does GWAS stand for ?
Genomic-wide associated studies
Produce proteins that keep cancer formation in check
What are tumor suppressor genes?
In the nose to treat lung cancer and other respiratory illnesses; anticancer drugs; anesthetics for pain management
Mist sprays
This hormone is found in body fat and is released to help your body maintain your normal weight.
What is leptin ?
The CA 125 antibody is in?
Ovarian cancer
What are used for scientists and physicians evaluate a person's genetic information are rapidly changing
Sequencing tools
Is the area of science involved in designing, building and manipulating structures at the nanometer scale
Nanotechnology
Injected with cancer cell antigens to stimulate immune system to attack cancer cells.
What are Cancer vaccines ?