CH9

1

100

B Cell receptor is made up of?

IgM, Ig(alpha), Ig(beta) chains

200

IgE mainly found where?

Connective tissue

300

How do Dimeric IgA and pentameric IgM transfer from one side of the cell to the other and how are they taken in by the cell?

Transcytosis and endocytosis

400

Interactions between which two cells are critical for survival of B cells?

B cells and follicular dendritic cells

500

Interaction of B cell CD40 and TFH Cell CD40 ligand gives rise to?

B Lymphoblasts (plasmablasts)

2

100

Naive B cells evolve into what type of cell in the adaptive immune response?

Highly active plasma cells

200

Bacterial toxins that commonly affect us are referred to as secreted and non-secreted toxins. What is the name for these toxins? (Hint: In/Out)

Endotoxin and exotoxins

300

Name of the area where B cells and TFH cell proliferates

Germinal Center

400

Most disease causing bacterial infections at mucosal surfaces are prevented by?

Neutralizing antibodies — remember they coat viruses and inhibit it’s attachment to human surfaces 

500

What does the germinal center contain? (ex: zones)

Mantle zone, centroblasts, Dark zone, light zone, & centrocytes

3

100

IgE’s main function is to defend us from what? (Hint: you eat bad sushi, what do you correlate bad sushi and stomach ache with)

Parasite infections

200

Do centrocytes with high affinity receptors survive and become plasma cells?

Yes

300

Where are IgG and dimeric IgA predominately in?

Extracellular fluid 

400

Isotype switching diversifies antibody function by:

changing the heavy chain C region

500

What is the main job of monomeric IgA, IgG, and IgM?

They protect the internal tissues and prevent blood borne diseases