Portals of Entry
Characteristics of Exo & Endotoxins
Define Infection Types
Carrier States
Koch's Postulates
100
Route of entry for an infectious agent; typically a cutaneous or membranous route.
What is portal of entry
100
Toxicity; Toxic in minute amounts
What is Exotoxin
100
Microbes enter the body, & remain confined to a specific tissue.
What is Localized Infection
100
Infected but show no symptoms of disease, such as genital herpes with no lesions.
What is Asymptomatic carriers
100
A procedure to establish the specific cause of disease.
What is Koch's postulates
200
___________ _____________ enters through both the respiratory and gastrointestinal tracts.
What is Mycobacterium tuberculosis
200
Toxicity; Toxic in high doses
What is Endotoxin
200
Infection spreads to several sites and tissue fluids, but may travel by other means such as nerves and cerebrospinal fluid.
What is Systemic Infection
200
Spread the infectious agent during the incubation period, like infectious mononucleosis.
What is Incubating carriers
200
Inoculate a susceptible healthy subject with the laboratory isolate and observe the same resultant disease.
What is Postulate #3
300
Pathogens in the genera ____________ and ____________ have adapted to invasion through several portals of entry such as the skin, urogenital tract, and respiratory tract.
What is Streptococcus and Staphylococcus
300
Is denatured by heat (60 deg)
What is Exotoxin
300
The initial infection.
What is Primary infection
300
Recuperating patients without symptoms; they continue to shed viable microbes and convey the infection to others, such as Hepatitis A.
What is Convalescent carriers
300
Find evidence of a particular microbe in every case of a disease.
What is Postulate #1
400
Portal of entry for Herpes simplex (type 1), gains access by:
What is Mucus membranes of the lips.
400
Manner of release; Can be released by cell via shedding or during lysis.
What is Endotoxin
400
Infection comes on rapidly, with severe but short-lived effects.
What is Acute Infection
400
Individuals who shelter the infectious agent for a long period after recovery because of the latency of the infectious agent such as Tuberculosis, and typhoid fever.
What is Chronic carriers
400
Re-isolate the same agent from this subject.
What is Postulate #4
500
HIV, Tichomonas, Candida albicans, hepatitis B, syphilis, gonorrhea, chlamydia, herpes, genital warts. (portal of entry)
What is Urogenital Tract
500
Typical source; Has a few gram-positive and gram-negative.
What is Exotoxins
500
Infection that progresses and persists over a long period of time.
What is Chronic Infection
500
Medical and dental personnel who must constantly handle patient materials that are heavily contaminated with patient secretions and blood risk picking up pathogens mechanically and accidentally transferring them to other patients.
What is Passive carriers
500
Isolate that microbe from an infected subject and cultivate it in pure culture in the laboratory; perform full microscopic and biological characterization.
What is Postulate #2