Bacterial Gene Regulation
Consists of an operator, promoter, and the genes they control
What is an operon?
What is Histone Acetylation?
Promotes transcription by modifies the chromatin structures (relaxin it).
What are siRNAs?
Another class of small RNAs that are similar in size and function to miRNAs
what is te competition mechanism of repressor?
Both the activator and the repressor recognize the activation site on the DNA and compete for binding to prevent transcription activation.
When glucose are present and lactose are absent...
CAP activator cannot bind to the activator site and the repressor binds to the operator and blocks the start of transcription.
What type of nucleosome modifications are possible?
Phosphorilation, methylation, acetylation, ubiquitination and citrullination
miRNA need form an secondary structure for can be activated. TRUE or FALSE
FALSE
What is te inhibition mechanism of repressor?
The repressor recognizes its DNA binding site, after that, the repressor binds to the activator and prevents it from promoting transcription.
Acts as the corepressor in the Trp operon
What is Tryptophan?
What is Alternative RNA Splicing?
Responsible for expanding the human genome
Each miRNAs are specific and unique for each mRNA
TRUE OR FALSE
FALSE
When the repressor binds to transcription initiation complex?
direct repression
In the lac operon, is needed to turn on the operon by inactivating the repressor by..
recognizing lactose or allolactose
What kind of domains have an activator?
activation domain and DNA-binding site domain
What is a microRNA?
Small single-stranded RNA molecules that are capable of binding to complementary sequences in mRNA molecules
When the repressor favour the action of histone deacetylase?
Indirect repression
About the lac operon, what are the consecuence when high lactose and glucose absent?
Strong transcription
What is Epigenetics?
The study of how environmental and behavioral factors affect how genes work, without changing the DNA sequence.
How some cells use the siRNA as defense mechanism?
With the help of Argonaute protein, the siRNA can binds to viral mRNA in order to favored their degradation
What is a signaling patway?
Cell signaling involves the transfer of information between molecules of cell in response to external or internal cues, consecuently the gene expression are modified.