Characteristics of Adaptive Immunity
Non-Self Foreign.
What is an antigen?
This is the basis for understanding the recognition of antigen.
What is cluster of differentiation?
Antibody is also known as this.
What is immunoglobulin?
Responsible for biologic function of antibodies.
What is Crystalline fragment?
This consists of antigen recognition molecules responsible for recognition and binding of membrane associated IgM and IgD.
What is B cell-receptor complex?
This produced by stromal cells is critical in driving the further differentiation and proliferation of B cells.
What is IL-7?
T and B cells.
What is a lymphocyte, adaptive immunity, primary lymphoid organs?
An antigen that can trigger an immune response.
What is Immunogenic antigen?
Most abundant class.
What is IgG?
Antigen binds by amino acids and the framework looks like this common structure.
What is a lock and key?
Referred to as CD3.
What are accessory proteins for intracellular signaling?
This process related to T-cells begins at birth and proceeds throughout life.
What is Clonal selection?
Spleen and lymph nodes.
What is secondary lymphoid tissue?
Antigen’s binding site.
What is an epitope?
IgA subclass predominantly in the blood?
What is IgA1?
Two light chains and two heavy chains are held together with this bond in a polypeptide chain.
What is a disulfide bond?
Highly specialized cells that manage/process some types of antigens.
What are Antigen-presenting cells?
Help the antigen-driven maturation of B and T cells.
What are helper T cells?
Antigen is processed and presented to immune cells by APC (antigen presenting cells) for presentation to this.
What are helper T cells (Th Cells)?
Antibody binding site.
What is paratope?
First antibody in an immune response.
What is IgM?
Acts as a recognition site for antigenic determinants, two identical fragments.
What is an antigen binding fragment?
In major histocompatibility complexes, these classes represent endogenous protein antigens.
What are A, B, and C?
This is necessary for proper differentiation of T Helper lymphocytes to occur.
What are costimulatory molecules?
Respond rapidly and efficiently on subsequent exposure to the same antigen.
What is humoral and cellular immunity?
If an antigen is large it is extremely is known to have this ability.
What is immunogenic?
Least concentrated immunoglobulin that mediates common allergic responses and defends against parasites.
What is IgE?
Valence of IgG, IgD, circulating IgA, and IgE.
What is 2?
Donor testing.
What are major histocompatibility or human leukocyte antigens?
The changing of classes is also known as this.
What is class switch?