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Basic Information on the Buffered Tablets
Concepts of Buffering
Chelation Therapy 1
Chelation Therapy 2
Interesting Facts
100
Which acid in fat soluble form is found in the stomach?
Acetylsalicyclic Acid
100
Are buffering agents made up of acids or bases?
Buffering agents can be both weak acids and bases.
100
Define Chelation Therapy
Chelation Therapy is the formation of two or more separate coordinate bonds between a polydentate (multiple bonded) ligand and a single central atom.
100
What is the aconim for OTC. Sentence: U.S. Food and Drug Administration unapproved "OTC"
OTC = Over the Counter
100
What will help release the aspirin and buffer?
Gum will help release the aspirin and buffer.
200
Why can Acetylsalicylic acid diffuse underneath the stomach lining?
The Acetylsalicylic acid can diffuse underneath the stomach lining because the cell membrane is a bi-lipid layer.
200
What are buffers?
A buffer is an aqueous solution that has a highly stable pH. If you add acid or base to a buffered solution, its pH will not change significantly.
200
A Ligand binds to ___________ to form a ________________
1) central metal atom 2) coodination complex
200
What are the four types of side effects that chelation may cause?
1) Headache 2) Nausea 3) Fever 4) Skin Reaction
200
What are other products that help relieve headaches and what does the substance contain.
Almonds help relieve headache because it contains substances like aspirin. It contains large amount of salicin and alcoholic glycoside.
300
Why won't the tablet not be able to diffuse back into the stomach?
The tablet will not be able to diffuse back into the stomach because the cell's pH is around 7 which is neutral, therefore it ionizes and becomes water soluble.
300
What will happen if hydrogen ions added to a solution incorporated with a buffer?
The buffers will absorb the hydrogen ions and will not allow for a change in pH.
300
Chelators are used in producing ... (LIST 4 ITEMS)
1) Shampoos 2) Fertilizer 3)Medicine 4) Food Supplements
300
What will happen if chelating agent was given to someone when not needed and who is it supported by?
It will cause Cognitive Damage and it is supported by the research done on rats.
300
What is the name of the "alcoholic glycoside" that has an effect on pain relief?
The name of the alcoholic glycoside is called "Salicin"
400
What does aspirin suppress?
Aspirin suppresses prostaglandins hormones that stimulates blood clotting.
400
What helps acetylsalicyclic acid prevent stomach ache?
Keeping acetylsalicyclic acid in ionic form helps prevent stomach ache.
400
How much was chelating agents market expected to reach in 2018? Also, name a chelator that is used in antibiotics.
Chelating agents market is expected to reach more than 5 million tonnes in 2018. Antibiotics name : TETRACYCLINE
400
Death was caused due to __________ caused by _______________ during chelation therapy.
1) Cardiac Arrest 2) Hypocalcaemia
500
Draw the structural diagram of aspirin on the black board. (hint: IUPAC name)
Look at Sheet
500
Why are Buffering agents added to the tablets? What are the buffering agent used in the process? What will happen when aspirin reaches the small intestine?
Buffering agents is added to the tablet to maintain the pH of the aspirin in the stomach.Buffering agent that is use in antacids, for example, MgO. When aspirin reaches the small intestine, it will start to dissolve and absorbed by the small intestine.
500
_____________ acid is recommended to be used for the treatment of lead poisoning.
Dimercaptouccinic acid