Treatment Modalities
A therapy that provides localized treatment of cancer, resulting in lethal and sublethal damage to cellular DNA. A) Chemotherapy B) Surgical Therapy C) Radiation therapy D) Biologic & Targeted Therapy
C) What is radiation therapy
Inflammation and ulceration of the mucous membranes lining the mouth and gastrointestinal track is know as...
What is mucositis
1) anticipatory (before treatment starts) 2) acute (within 1 hour) and 3) delayed (24 hours or more after treatment)
...are 3 ways this side effect might be manifested
What is nausea (or chemo induced nausea & vomiting)
The use of chemicals to treat a disease
What is chemotherapy
When this type of care is provided (sometimes through chemotherapy administration), the goal is to improve quality of life...the goal of this type of care is not cure control.
What is palliative care
This type of treatment/therapy is manmade, produced in a lab and targets specific molecules (antigens) on the cancer cell. All drugs in this category end in ...mab
What are monoclonal antibodies
Which of the following is not a common side effect of cytotoxic drugs:
A) Vomiting B) Alopecia C) Nausea D) Increased bone marrow production
What is D - increased bone marrow production
Uncontrolled cell division and _________ to other body parts are identifying characteristics of cancer cells present in the body.
What is metastasis
Chemotherapy is given prior to other treatment modalities (usually surgery) in hopes of shrinking the tumor, making the therapy that follows, more effective.
What is neoadjuvant
Which of the following is the medical term for hair loss: A) Alopecia B) Anaphylaxis C) Apoptosis D) Asparagine
What is A - Alopecia
A systemic, targeted therapy which is usually non-curative and rarely used as a single agent. It is used most often in breast and prostate cancer.
What is hormone therapy
When this happens during chemotherapy administration, tissue damage can occur at the IV site. Patients often complain of pain or a burning sensation.
What is extravasation
Chemotherapy works is this manner/is called this when it is given to increase the effects of radiation therapy.
What is a radiosensitizer
The goals of treatment with chemotherapy
What is Cure, Control, or Palliation
A cutaneous reaction that sometimes occurs when certain chemotherapy (or immunologic agents) are administered following radiotherapy.
What is radiation recall (dermatitis)
Term used to describe the method of administration when chemotherapy and radiation therapy are given, but one treatment is given after the other is done (e.g., they are not given @ the same time).
What is sequential administration
This side effect of chemotherapy is potentially life-threatening and can be a dose-limiting factor in chemotherapy dosing.
What is infection (neutropenia)
Tumor cell proliferation is not linear, what is the name of the growth pattern of cells (initially exponential, eventually plateaus)
What is Gompertzian (the Gompertzian model)
This class of chemotherapy drugs kill only those cancer cells which are undergoing division (actively dividing). They do not affect cells in the resting (G0) phase.
What are: Cell cycle (phase) specific chemo drugs
True or False:
The doubling time is the same for all types of cancers/tumors
What is false. Very aggressive tumors can have a doubling time of 60 days whereas a non-aggressive tumor may have a doubling time of 100 days.
The goal of each chemotherapy treatment is to: A) Eradicate all of the cancer cells B) Eradicate all the actively proliferating cells in the body C) Eradicate the wall of the cancerous tumor D) Eradicate a percentage of the cancer cells
What is D - Eradicate a percentage of the cancer cells
The name given when suppression of this system results in damage of the pool of stem cells (often resulting in neutropenia, anemia and thrombocytopenia.
Bone marrow suppression; suppression of the hematopoietic system; or myelosuppression.
The lowest point the counts reach following chemotherapy. Usually occurs between day 7-10 (sometimes takes longer).
What is nadir
The use of more than one chemotherapy agent at a time to treat cancer. The intent is to decrease resistance and to increase cell kill without compounding toxicities.
What is combination chemotherapy
Which of the following is correct about the rate of cell growth in relation to chemotherapy? A) Faster growing cells are less susceptible to chemo B) Non-dividing cells are more susceptible to chemo C) Faster growing cells are more susceptible to chemo D) Slower growing cells are more susceptible to chemo
What is C - Faster growing cells are more susceptible to chemo