Cleviprex
The indication for Cleviprex
What is to reduce blood pressure when oral therapy isn’t feasible or desirable
The bolus dose of Kengreal
What is 30mcg/kg
This is the number of neurons lost per minute during stroke
What is 1.9 Million
This is what ‘PCI’ stands for
What is percutaneous coronary intervention
This is the COR and LOE for antiplatelet therapy for patients undergoing PCI
What is 1 and A
1000mL per 24 hours
What is the 24hr lipid load restriction?
Significant active bleeding and hypersensitivity
What are the contraindications for Kengreal?
It’s the standard ASA/AHA quality metric for door-to-needle time for IV fibrinolytic therapy
What is 60 Minutes
The most commonly blocked artery
What is the LAD (left anterior descending)
This is the COR & LOE for IV P2Y12 inhibition
What is 2b, B-R
This is the concentration of Cleviprex per ml
What is 0.5mg/mL?
The stability of Kengreal
What is 12 hours in 5% dextrose injection and 24 hours in Normal Saline at room temperature
According to the CDC, this is the number of people that have stroke each year in the US
What is 795,000
According to Yale Medicine, this is the number of yearly PCI performed in the US
What is 900,000-1,000,000
What are clipping and coiling
This is how long a patient should be monitored for rebound hypertension after Cleviprex infusion is stopped
What is 8 hours
In Champion Phoenix, this group represented 18% of patients
What is > or = to 75 years old
Every ___ seconds, a person has a stroke
What is 40
This is the percentage of STEMI PCI that require stents
What is 80%
For patients with mild to moderate spontaneous ICH and SBP >___mmHg, acute lowering to <___mmHg may be harmful
What is 150 & 130
In clinical trials, this was the max Cleviprex overdose
What Is 106mg/hr
In Champion Phoenix, this was 0.3% in the Kengreal group, and 0.1% for clopidogrel
What is the rate of discontinuation for bleeding events
The acronym F.A.S.T stands for these four things to look for to indicate a potential stroke
What is Face (drooping), Arms (can they lift both), Speech (slurred), T (time- call 911 immediately)
The year that PCI was invented
What is 1977. It was pioneered by Andreas Grüntzig
For patients with elevated BP that otherwise would be candidates for IV alteplase treatment, it’s recommended that their BP be carefully lowered to SBP _______, and DBP to ________ before initiating IV fibrinolytic therapy
What is <185 mm Hg and <110 mm Hg