Chronic Myeloid Leukemia

treatments

100

In the past chemotherapy has been used to treat CML, but now it is seen that this targeted therapy is more effective?

TKIs

200

CML treatments are based on how many __________ white blood cells are present and how ____________ the disease is behaving.

immature 

aggressively 

300

There are occasions in which immunotherapy is seen as the best course of treatment for CML. One of these situations is?

pregnancy 

risk factors

100

This gender is more commonly seen diagnosed with CML.

females

200

While CML may be seen at all ages, ________ is the average age of diagnosis.

66

300

The philadelphia chromosome is seen as the primary cause of CML. What type of chromosomal damage occurs to create this gene?

tanslocation

spread

100

CML starts in these specific cells located in the spongey bone.

myeloid

200

CML starts in the bone marrow but can travel. What two places does it most commonly go?

blood then lymph

300

These three phases of CML can be remembered by the acronym CAB.

Chronic, Accelerated, Blast

side effects

100

When platelet counts drop its thrombocytopenia, when red blood cell counts drop its anemia. What is it called when white blood cell counts drop?

leukopenia

200

CML interferes with normal blood cell counts, which leads the patients to become immunosuppressed. This side effect leaves patients at a high risk of _________?

infection

300

Three of the most common symptoms associated with anemia are?

fatigue, weakness, dyspnea

random

100

This term refers to the way CML grows slowly over time.

chronic

200

Rather than the traditional TNM staging system, the progression of CML is discussed in terms of?

phasing 

300

Different cancers have specific testing that can be completed to aid in diagnosis. For example PSA and CEA. What specific testing is associated with CML?

FISH