Opthalmology
Location which the oculomotor, trochlear, trigeminal and Abducens nerve sits
What is the Cavernous sinus
Lack of suppression with high dose dexamethasone
What is ACTH-dependent Cushing Syndrome (ectopic source of ACTH)
Antibody involved in Urticaria reaction
What is IgE
Disease where brain shows cortical atrophy, decreased hippocampal and temporal mass and enlargement of the cerebral ventricles
Transcription factor which up-regulates the EPO gene in response to tissue hypoxia
What is HIF-1 hypoxia-inducible factor 1
Area of partial alteration in field of vision consisting of partially diminished or entirely degenerated visual acuity that is surrounded by a field of normal vision
What is scotoma
Hormones secreted by acidotropes
What is Prolactin and Growth Hormone
Risk increased with presence of CDNK2A and CDK4
What is familial melanoma
Positive reinforcement (addiction) of substances often results from the release of dopamine in this area of the brain
What is nucleus accumbens
Substance released in the setting of chronic disease which inhibits ferroportin and iron release from macrophages in order to reduce available iron for infective bacteria
What is hepcidin
Refractive error fixed with concave lens
What is myopia
Medication which blocks thyroid peroxidase and risk of agranulocytosis
What is carbimazole
Breslow thickness greater than this depth suggests invasion into the papillary dermis
What is 0.75mm
Duration required for a diagnosis for schizophrenia
What is 6 months
Likely diagnosis in setting of atypical lymphocytes, sore throat, fever, anorexia, lethargy, jaundice, dehydration, maculopapular rash, generalised lymphadenopathy and hepatosplenomegaly.
What is infectious mononucleosis, EBV infection
Genetic predisposition involved in ophthalmic condition with mutton fat keratic precipitates and hypopyon
What is HLA-B27
Pathogen which can cause erysipelas, fever alongside a painful, red rash with rapidly advancing demarcated edge.
What is S. pyogenes
Treatment of hyperkeratotic disorders by reduction of keratinocyte adhesion by disrupting intercellular junctions in the stratus corneum
What is salicylic acid
Indirect activator of GABAa R which increases the opening frequency of Cl- channels leading to reduced neuronal excitability.
What is Benzodiazepine
Disease which results in the symptoms hypercalcemia, renal insufficiency, anaemia and bone disease.
What is multiple myeloma
Embryological origin of the lacrimal gland
What is surface ectoderm
Enzyme deficiency resulting in reduced cortisol, aldosterone and androgens leading to female external genitalia, intra-abdominal testis and delayed puberty or sexual infantilism.
What is 17aplha-hydroxylase
Pathology managed with Minoxidil
What is androgenetic alopecia
NMDA R antagonist and GABAa R agonist which reduces cravings in alcohol dependant patients
What is acamprosate
Common genetic mutation in myeloproliferative neoplasms; polycythaemia vera, essential thrombocytopenia and primary myelofibrosis
What is JAK2