Viale-A Study
Safety
DiNardo Video
Tibsovo
North Central Region
100

1.3 months

What is the median time to first response?

100

Patients received an average of __ cycles of AZA+VEN compared to ___ controlled arm.

What is 7 and 4.5?

100

3 Quarters of patients experienced this _______. Management strategy is important to understanding treatment of Ven + AZA

What is dose interruptions?


100

Name of Tibsovo combination study

What is AGILE?

100
Steve Vickers word

What is enamored? 

200

Incidence of composite remission in IDH1 or IDH2 mutations patients receiving AZA+VEN

What is 75.4%?

200

42%

What is the Febrile Neutropenia and Neutropenia rates?

200

Phase 1 data presented by Polleya was ____ at ASH 2019. Phase 3 findings were ____ of the AZA + VEN arm.

What is 71% and 66.4%?

200

Average age for our IC ineligible monotherapy study

What is 77?

200

Brian and his wife do this once a week (Please keep PG!!)

What is Margarita Mondays?

300

Number (percent) of patients who received AZA+VEN had a first response before the initiation of cycle 2 

What is nearly half or 43%?

300

Number of patients experienced in TLS AZA+VEN arm? and in what cycle of treatment

What is 3 and 1st cycle?

300

What day does Dr. DiNardo do Cycle 1 Bone Marrow and how often does she do them after Cycle 1

What is Day 24-25 and every 2-3 months?

300

Median time to CR or CRh in IC-ineligible Tibsovo patients

What is 2.8 months?
300

What is Richelle's company car?

What is a Volkswagen Jetta?

400

Dosing for Venetoclax for mitigation of the Tumor Lysis syndrome during cycle 1

What is 100mg day 1, 200mg day 2, on day 3 target dose of 400mg was reached and continued until day 28?

400

Primary reasons for dose interruptions

What is neutropenia, febrile neutropenia, and thrombocytopenia? (Myelosuppression)

400

What was outcome of R/R AML after Frontline HMA + VEN in months?

What is 2.9 months OS?

400

Tibsovo enabled a decrease in the percentage of bone marrow blast and an increase in neutrophil counts for some patients by the end of 

What is Cycle 1?

400

Ken's Polar Plunge Number

What is 14?
500

Bone Marrows Assessments performed

What is end of cycle 1 and every 3 cycles thereafter until two consecutive samples confirmed of CR or CRi

500

What percent of patients received AZA+VEN modifications to the duration of Venetoclax?

What is 53%?

500

Physician's use to never give to myeloid diseases due to the thought process it would stimulate myeloid disease but now is given after 1st cycle of Ven + AZA by some physicians.

What is GCSFs?

500

Median duration of exposure to Tibsovo was ___ in the IC-ineligible patients

What is 4.3 months?

500

2022 Super Bowl Champions

What is Kansas City Chiefs?