Pathophysiology
History & Physical Exam
Differential diagnosis
Investigations
Management
100

This mechanism causes edema due to increased hydrostatic pressure in heart failure.

What is increased venous pressure?

100

Unilateral leg swelling raises concern for this life-threatening condition.

What is DVT?


100

Bilateral leg swelling with dyspnea and orthopnea suggests this diagnosis.

What is congestive heart failure?

100

First-line imaging for suspected DVT.

What is Doppler ultrasound?

100

First-line non-pharmacologic treatment for venous insufficiency.

What are compression stockings?

200

Loss of this plasma protein leads to decreased oncotic pressure and edema.

What is albumin?

200

This exam finding helps differentiate lymphedema from venous edema.

What is non-pitting edema?

200

Leg swelling following lymph node dissection is most likely due to this.

What is lymphedema?

200

This lab test is often low in patients with nephrotic syndrome.

What is serum albumin?

200

Immediate management for suspected DVT.

What is anticoagulation?

300

Edema caused by increased capillary permeability is commonly seen in this condition.

What is inflammation?

300

Edema that worsens at the end of the day and improves with elevation suggests this cause.

What is venous insufficiency?

300

Sudden unilateral swelling after surgery or prolonged immobilization.

What is DVT?

300

Elevated levels of this peptide suggest heart failure.

What is BNP?

300

This class of drugs is used to treat edema in heart failure.

What are diuretics?

400

This Starling force change explains edema in cirrhosis.

What is decreased oncotic pressure?

400

Skin changes such as hyperpigmentation and lipodermatosclerosis point to this diagnosis.

What is chronic venous insufficiency?

400

Edema with nephrotic-range proteinuria is caused by this renal condition.

What is nephrotic syndrome?

400

This urine finding supports nephrotic syndrome.

What is proteinuria (>3.5 g/day)?

400

Mainstay treatment for lymphedema.

What is compression therapy and physiotherapy?

500

Non-pitting edema results from accumulation of this substance in tissues.

What are glycosaminoglycans (mucopolysaccharides)?

500

Inability to pinch the skin at the base of the second toe is called this sign.

What is Stemmer sign?

500

Pretibial non-pitting edema associated with this endocrine disorder.

What is Graves disease?

500

This imaging modality helps evaluate chronic venous insufficiency.

What is venous duplex ultrasound?

500

Diuretics are generally ineffective for this type of edema.

What is lymphedema?