Don't be a DOPE-amine
This DA receptor subtype is most associated with positive symptoms in schizophrenia
D2
This type of neuron is primarily associated with inhibition
interneuron
Lewy Body dementia differs from Alzheimer's disease in that this symptom appears much later in LD
memory problems
A diagnosable manic episode must last at least one week unless this criteria occurs
Hospitalization
Mutations in the FMR1 gene are assocaited with which autism related disorder?
Fragile X Syndrome
D1 receptor activity is downregulated in this area of the brain in schizophrenia
frontal cortex
This hypothesis in schizophrenia involves an imbalance in excitation/inhibition
NMDA hypothesis
Vascular dementia (strokes) occur in these two forms:
ischemic and hemorrhagic
The monoamine hypothesis can't be the whole story for depression because antidepressants take this long to start working
Two weeks
All the genetic disorders associated with autism have this physiological abnormality in common
Dendritic spine abnormalities
The nigrostriatal pathway is associated with what type of medication effects in schizophrenia
side effects
The VPA mouse model of autism hypothesizes that the development of this neurotransmitter system is abnormal
GABA
Beta amyloid is toxic in that it activates this system in the brain
immune system
Most brain areas in depression show decreased activity, except for this area, which shows increased activity
Anterior cingulate
The gene MECP2 in Rett Syndrome is involved in what basic function
Chromatin remodeling
typical antipsychotic medications primarily function via this mechanism of action
D2 receptor antagonist
These neural structure are packed too tightly in autism, resulting in increased spread of excitation in the cortex
Minicolumns
Treatment for Alzheimer's disease currently targets these two neurotransmitter systems
Acetylcholine and glutamate
The HPA axis hypothesis of depression involves repairable damage to this brain structure
Hippocampus
This gene is associated with Phelan McDermid syndrome and scaffolding protein regulation
D2 receptors in the basal ganglia inhibit this enzyme
adenylate cyclase
Dopamine from this area of the brain can modulate the excitation/inhibition imbalance in schizophrenia, creating interaction between the two main hypotheses for SZ
VTA
These are the three main brain abnormalities associated with Alzheimer's disease
Enlarged ventricles, amyloid plaques, neurofibrillary tangles
This is the ion channel mechanism of action for benzodiazapines in reducing anxiety
GABA agonist
Tuberous sclerosis and PTEN syndrome both have to do with regulation of this pathway
mTOR