Dupixent Deep Dive
Dupixent Targets Two Key Cytokines Involved in Type 2 Inflammation
What are IL-4 & IL-13
This Topical PDE-4 Inhibitor is Approved for Mild-to-Moderate Atopic Dermatitis and is Often Prescribed Before Patients Advance to Systemic Therapy
What is Zoryve?
This City is Known as the "Magic City" & is the Largest Metropolitan Area in South Florida
What is Miami?
This Cultural Phenomenon starring Margot Robbie became the highest grossing film of 2023
What is Barbie?
This Common Dermatology Score Measures Eczema Severity from 0 (clear) to 4 (severe)
What is IGA (Investigator's Global Assessment)?
Dupixent is Administered Using this Route of Administration
What is Subcutaneous Injection?
Unlike Dupixent, these Oral Medications Carry Boxed Warnings for Serious Infections, Malignancy, Major Adverse Cardiovascular Events, Thrombosis & Mortaliity
What are JAK inhibitors?
This National Park, Located in South Florida is the Largest Subtropical Wilderness in the United States
What is Everglades National Park?
This Singer is Known for the hit songs "Fireball" & "Give me Everything" and Proudly Represents Miami
Who is Pitbull?
This Term Refers to the Healthcare Pathway that Helps Patients Access Therapy Through Benefits Verification, Prior Authorizations & Specialty Pharmacy Coordination
What is HUB (or patient support services program)?
This is the Lowest Approved Age Group at which Dupixent can be used for AD, PN, CSU & BP?
What is 6 months of age (AD), 18 (PN), 2 (CSU), 18 (BP)
These Two Biologics Targets IL-13 alone, while Dupixent Inhibits Signaling from both IL-4 & IL-13
What is Adbry & Ebglyss
This Famous 113-Mile Highway Connects Mainland Florida to Key West through a Series of Islands & Bridges
What is Overseas Highway?
This Singer was Known as the "Princess of Pop"
Who is Britney Spears?
This Acronym Refers to Antibodies Designated to Neutralize a single Cytokine
What are mAbs (monoclonal antibodies)?
This Adverse Event is one of the most Frequently Reported in Dupixent Clinical Trials
What is Conjunctivitis
This Cytokine Pathway is the Primary Target of Nemluvio and is Often Referred to as the "Itch Pathway" in AD & PN
What is IL-31
This is Florida's State Bird
What is the Mocking Bird?
This Singer's 2024 Hit "Espresso" Helped Launch her into Pop Superstardom
Who is Sabrina Carpenter?
This Regeneron position supports the field sales organization by helping them operate more effectively, consistently & compliantly. Reporting directly to the NBD
FFE (Field Force Effectiveness)
Dupixent Binds to this Receptor Subunit, Inhibiting Signaling from Both IL-4 & IL-13
What is IL4 Receptor Alpha (IL-4Ra) subunit?
While Dupixent Targets IL-4 and IL-13 signaling, Rhapsido directly targets this pathway responsible for Histamine Release from Mast Cells & Basophils
What is the BTK Pathway?
Before Becoming a US Territory, Florida was Controlled by these two European Nations
What are Spain & Great Britain?
This Movie Won the Academy Award for Best Picture in 2024
What is Oppenheimer?
This 7-Day Composite Score is the Gold Standard in Chronic Spontaneous Urticaria & Combines Itch Severity & Hive Count to Assess Overall Disease Activity Over Time
What is UAS7 (Urticaria Activity Score over 7 Days)?