Signs and Symptoms
Nutritional Consequences
Dietary Non-compliance
Consequences
Intestinal Damage Correlation w/ Features
100

This describes the flattening of the finger-like projections that absorb nutrients that causes malnutrition in coeliac.

What is villous atrophy?

100

This mineral is absorbed in the duodenum, and its malabsorption causes the microcytic, hypochromic anaemia seen on Maeve's FBE. 

What is iron?

100

A common consequence of dietary non compliance in celiac patients.

What is malnutrition?

100

Damage to this section of the bowels leads to the most prominent fat-soluble nutrient deficiencies and associated conditions.

What is the terminal ileum?

200

This itchy, blistering skin condition is caused by anti-TTG IgA antibodies, and is considered the cutaneous manifestation of coeliac disease

What is dermatitis herpetiformis?

200

These two parts of the bowels are responsible for absorbing folate and Vitamin B-12 respectively.

What are the proximal jejunum and terminal illeum?

200

A teenager with poorly controlled celiac disease appears to be developing more slowly than their peers. Chronic intestinal damage and inadequate nutrient absorption can contribute to this condition.

What is delayed puberty / faltering growth?

200

This physiological type of diarrhoea occurs in coeliac disease due to fluid being drawn into the bowel lumen by unabsorbed nutrients.

What is osmotic diarrhoea?

300

Despite generalised abdominal tenderness, these three findings were notably absent on Maeve's abdominal exam, helping rule out an acute surgical abdomen.

What are rebound tenderness, guarding, and hepato/splenomegaly?

300

Maeve's stool sample was described as greasy and poorly formed; this term describes her stools, caused by fat malabsorption due to loss of absorptive surfaces.

What is steatorrhea?

300

Long term dietary non-compliance can increase the risk of this condition due to poor intestinal absorption of calcium and vitamin D.

What is osteoporosis?

300

Damage to enterocytes and loss of this enzyme explains why many newly diagnosed coeliac patients also can't tolerate products like cheeses and yoghurts.

What is lactase?

400

This gait and coordination disorder can result from coeliac disease either via vitamin E deficiency or as a direct immune-mediated neurological complication.

What is gluten ataxia?

400

This trace element deficiency in coeliac disease can contribute to loss of taste, poor wound healing, hair loss, and impaired immune function.

What is zinc?

400

A patient with celiac disease has numbness and tingling in their hands and feet despite reporting minimal digestive symptoms, due to poor absorption of this vitamin.

What is Vitamin B12?

400

Malabsorption of calcium and vitamin D in coeliac disease can trigger this compensatory hormonal response, contributing to bone demineralisation.

What is secondary hyperparathyroidism?

500

This liver finding (mildly elevated ALT and AST without another clear cause) can be an extra-intestinal manifestation of coeliac disease that normalises on a gluten-free diet. 

What is coeliac hepatitis?

500

A deficiency in this vitmain can impair clotting and contribute to bruising or bleeding in untreated coeliac disease.

What is Vitamin K?

500

Unexplained weight loss, persistent fatigue, and intermittent night sweats in a person with poorly controlled celiac disease may indicate this rare but serious complication.

What is intestinal lymphoma?

500

This compensatory histological change occurs alongside villous atrophy, as crypts increase cell turnover to replace damaged enterocytes.

What is crypt hyperplasia?