Of the following, this is NOT an effect of erythropoietin: 1. Increased BFU-E cell proliferation. 2. Increased CFU-E programmed cell death. 3. Increased hemoglobin synthesis. 4. Increase erythroid differentiation. 5. Reticulocytosis
What is increased CFU-E programmed cell death? (CFU-E programmed cell death is inhibited)
100
This is the average lifespan of an erythrocyte in circulation.
What is 120 days?
100
Thallassemia
What is a cause of microcytic anemia?
100
HGB is an abbreviation for this.
What is hemoglobin concentration?
100
Abnormally low hemoglobin concentration in whole blood
What is anemia?
200
This vital organ produces EPO.
What is the kidney?
200
This erythrocyte precursor is released into circulation after ~48 hrs. of hematopoiesis and ~24 hrs. in cases of anemia.
What is a reticulocyte?
200
Vitamin B12 deficiency
What is a cause of macrocytic anemia?
200
Used synonymously with packed red cell volume (PCV)
What is hematocrit (or HCT)?
200
HGB, HCT, RBC are low compared to reference range.
What is anemia?
300
These cells have EPO receptors which when activated by binding EPO, stimulates erythropoiesis.
What is the bone marrow?
300
Premature release of reticulocytes is called this.
What is reticulocytosis?
300
Folate deficiency
What is a cause of macrocytic anemia?
300
Measures average volume of an erythrocyte
What is Mean Corpuscular Volume (MCV)?
300
Loss of sensation, low HGB, high MCV, normal MCHC, normal CR
(Question: What is _______ anemia caused by __________?)
What is macrocytic anemia caused by decreased DNA synthesis?
400
Aside from a healthy kidney and responsive bone marrow, this is required for proper erythropoiesis and RBC development.
What is the adequate nutrition?
400
This descendant of a hematopoietic stem cell has no DNA nor RNA.
What is an erythrocyte or RBC?
400
Iron deficiency
What is a cause of microcytic anemia?
400
(Patient HCT/Mean normal HCT) x OR
What is Corrected Reticulocyte count (CR)?
400
Low HGB, low MCV, low MCHC, low CR (Question: What is _______ anemia caused by __________?)
What is microcytic anemia caused by iron deficiency?
500
(FYI) A 2003 study showed that women have a LOWER, EQUAL or GREATER chance of survival from breast cancer when taking EPO.
What is lower?
500
Edward is anemic. The result of this CBC test for Edward is normal which indicates that Edward’s response to the anemia is abnormal.
What is CR?
500
Acute blood loss
What is normocytic RBC? Will also accept: What can cause slightly macrocytic anemia?
500
MCH/MCV x 100
What is mean corpuscular hemoglobin concentration (MCHC)?
500
Low HGB, normal MCV, normal MCHC, high CR
What is anemia caused by acute blood loss or premature red cell destruction?