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Tour de Doping
Edward, Jacob, Bella
Small, large or just right?
test score meaning
What's wrong with me, doc?
100
Erythropoietin helped this Texan to victories in the Tour de France. (FYI)
Who is Lance Armstrong?
100
This is the average lifespan of an erythrocyte in circulation.
What is 120 days?
100
Thallassemia
What is a cause of microcytic anemia?
100
HGB is an abbreviation for this.
What is hemoglobin concentration?
100
Abnormally low hemoglobin concentration in whole blood
What is anemia?
200
This vital organ produces EPO.
What is the kidney?
200
This erythrocyte precursor is released into circulation after ~48 hrs. of hematopoiesis and ~24 hrs. in cases of anemia.
What is a reticulocyte?
200
Vitamin B12 deficiency
What is a cause of macrocytic anemia?
200
Also referred to as packed red cell volume (PCV)
What is hematocrit (or HCT)?
200
HGB, HCT, RBC are low compared to reference range.
What is anemia?
300
These cells have EPO receptors which when activated by binding EPO, stimulates erythropoiesis.
What is the bone marrow?
300
Premature release of reticulocytes is called this.
What is reticulocytosis?
300
Folate deficiency
What is a cause of macrocytic anemia?
300
Measures average volume of an erythrocyte
What is Mean Corpuscular Volume (MCV)?
300
Loss of sensation, low HGB, high MCV, normal MCHC, normal CR
What is macrocytic anemia caused by decreased DNA synthesis?
400
EPO-stimulated erythropoiesis is only effective in a person who has adequate nutrition, responsive bone marrow and at least one healthy _____.
What is the kidney?
400
This descendant of a hematopoietic stem cell has no DNA nor RNA.
What is an erythrocyte or RBC?
400
Iron deficiency
What is a cause of microcytic anemia?
400
(Patient HCT/Mean normal HCT) x OR
What is Corrected Reticulocyte count (CR)?
400
Low HGB, low MCV, low MCHC, low CR
What is anemia caused by iron deficiency?
500
EPO administration will result in LOWER, EQUAL or GREATER number of CFU-E cells.
What is greater?
500
Hypoxia induces kidneys to release this protein which induces RBC production.
What is erythropoietin or EPO?
500
Acute blood loss
What can cause normocytic anemia?
500
MCH/MCV x 100
What is mean corpuscular hemoglobin concentration (MCHC)?
500
Low HGB, normal MCV, normal MCHC, high CR
What is anemia caused by acute blood loss or premature red cell destruction?