This disease of Persian cats results in a reduced number of dense granules and thus, abnormal platelet aggregation.
What is Chediak-Higashi Syndrome?
100
This X chromosome-linked recessive inherited disease is over-represented in male German Shepherds will cause a prolonged PTT.
What is Hemophilia A (Factor VIII deficiency)
100
This is the recommended treatment in a cat with Hageman deficiency.
What is nothing?
100
This medication may be given 30 minutes prior to surgery in a doberman with vWD to reduce the risk of hemorrhage.
What is DDAVP (desmopressin)?
100
Name the clotting factors in the intrinsic pathway.
What are XII, XI, IX, VIII?
200
This breed may display abnormal platelet aggregation in response to collagen (associated with a cyclic neutropenia).
What is the Gray Collie?
200
This factor deficiency more common in cats and will prolong the PTT but will not result in any clinical bleeding.
What is Factor XII (Hageman Factor) deficiency?
200
This product is prepared from fresh frozen plasma and contains a fivefold to tenfold concentration of active VWF in ~ 1/10th volume of the starting plasma.
What is cryoprecipitate?
200
These 2 breeds are the most commonly identified with Type II vWD.
What are the German Shorthaired Pointers and German Wirehaired Pointers?
200
Platelet activation by ADP leads to a conformational change in this platelet receptor that induces binding to fibrinogen.
What is GP IIbIIIa?
300
This autosomal recessive bleeding disorder caused by qualitative or quantitative deficiencies of the platelet membrane glycoprotein IIbIIIa occurs in the Great Pyrenees dog.
What is glanzmann's thrombasthenia?
300
This coagulopathy may be known as Christmas disease and generally results from <1% of normal factor activity and a prolonged PTT.
What is Hemophilia B (factor IX deficiency)?
300
This product is prepared by centrifugation of whole blood at a low G force and contains ~80% of the platelets, in 1/3 the volume of the starting whole blood unit.
What is platelet rich plasma?
300
This type of von Willebrands disease results from a low concentration or disproportionate loss of only the high-molecular weight multimers.
What is Type II vWD?
300
Plasma vWF:Ag in patients with Type III vWD is expected to be this percentage of normal.
What is <1%?
400
Scott syndrome is a rare hereditary bleeding disorder associated with an inability of stimulated platelets to externalize the negatively charged phospholipid, phosphatidylserine (PS). This has been identified in this dog breed.
What is the German Shepherd?
400
Stuart-Prower deficiency is due to a lack of this clotting factor and results in a prolonged PT and PTT.
What is Factor X?
400
Stored or frozen plasma is deficient in these 3 factors and is therefore not commonly used in coagulopathies.
What are factors V, VIII, and vWF ?
400
This size vWF multimer is the most hemostatically active.
What are the large multimers?
400
A beagle with a prolonged PT but normal PTT may have this autosomal dominant factor deficiency.
What is Factor VII deficiency?
500
Although the American Cocker Spaniel has a normal number of dense granules, they may be lacking this platelet agonist resulting in moderate to severe bleeding w/ trauma.
What is ADP?
500
This factor deficiency results from an autosomal recessive mode of inheritance identified in Kerry Blue Terriers and may result in variable bleeding tendency associated with trauma.
What is Factor XI deficiency?
500
This medication stimulates release of factor VIII from endothelial cells due to stimulation of the V1a receptor.
What is DDAVP (desmopressin)?
500
This is the mode of inheritance of Types II and III vWD.
What is autosomal recessive inheritance?
500
ADP, ATP, and serotonin are released from this part of a platelet.