Drugs
Stimulant medications for ADD/ADHD-Concerta, VyVanse, Ritalin
Injections
These glial cells contribute to the blood-brain barrier
Astrocytes
resembles habituation
tolerance
Group V; stimulants
This group of drugs, e.g. Klonopin, Xanax, should not be consumed with alcohol
Group I
Injection into the brain
Regulates the night-wake cycle
Pineal gland
More likely with periodic use
sensitization
Type of correlation between dependence and physical harm
Positive
Impair memory; GHB or "date rape" drugs
Group I
This route of entry explains why your arm gets sore after vaccines
Intramuscular
This area triggers vomiting when we have encountered a toxic substance
area postrema
In this type of tolerance, the number of enzymes needed to break down drugs in the liver, blood and brain increases
metabolic
The two natural sources of opioids:
Opium and the brain (endorphins)
"First" and "second" generation; first generation has unwanted side effects, like Tardive Dyskinesia
Group II, or antipsychotics
Because of this, less of the agent will reach systematic circulation, so more of the drug is needed
First pass effect
Master of the master gland
Hypothalamus
Responsible for the heroin overdose in the study we visited
Classical conditioning or change in environment; tolerance is classically conditioned
ETOH has a selective, depressant effect on what brain region?
Frontal lobe of the cerebral cortex
Historically called "narcotic analgesics"
Group IV; opioid analgesics
SEVEN ways that our body catabolizes
sweat, exhaled air, liver, breast milk, urine, feces and sequestered in fat cells
Two mechanisms for passing the blood-brain barrier
small molecules or active transport system
Brain cell activities adjust to minimize the effect of a drug
cellular tolerance
This class of hormones affects our stress response
Glucocorticoids