Viral
Daily dose of steroids given to patient's with stromal keratitis in HEDS trial?
8x/day
Name 6 bacteria/fungi that can invade an intact epithelium.
Fusarium CHANNLS
What is the primary finding in limbal VKC and what cell type is found within?
BONUS (+200): Name two procedural treatments for VKC and its complications
Horner-Trantas dots, eosinophils
BONUS: Supratarsal injection of corticosteroid and debridement of shield ulcer
Most common ocular finding in reactive arthritis?
BONUS: Skin eruption on palms and soles in this condition
Papillary conjunctivitis
BONUS: Keratoderma blennorrhagicum
This chemotherapy drug causes punctate keratopathy and refractory epithelial microcysts.
Cytarabine
What dose of oral acyclovir added to trifluridine and corticosteroids benefitted patients with stromal keratitis in the HEDS trial.
None; there was not found to be a benefit
Most common infectious cause of dacryoadenitis
EBV
According to the BCSC book, what is the procedural treatment for ocular SJS and what is the indication to escalate to this treatment?
Amniotic membrane transplant; ANY corneal, conjunctival, or eyelid margin defects
What is the Hutchinson triad? What disease does it refer to?
BONUS (+200): When syphilitic IK becomes opaque from deep corneal vascularization the exam finding is likened to a ___ ___ ?
Interstitial Keratitis, CN8 deafness, widely spaced peg-shaped teeth. Syphilis
BONUS: Salmon patch
What systemic disease is associated with SLK? Floppy eyelid syndrome?
Thyroid disease; OSA
A patient presents with anterior uveitis and endotheliitis presents with elevated IOP. Has a history of corneal transplant. HSV-1 and HSV-2 serologies are stone cold negative. What medication would you consider treating him with in addition to topical steroids and IOP-lowering drops?
Valgancyclovir
Most common culture media for acanthamoeba
BONUS (+300): Name culture media for fungi and mycobacteria, respectively
Acanthamoeba - Nonnutrient agar with bacterial overlay (E coli)
Fungi - Sabouraud dextrose, brain-heart infusion
Mycobacteria - Lowenstein Jensen
Anderson Krueger owns a thriving allergy practice in the Western North Carolina mountains. He has finally found a successful biologic treatment for one of his young patients with resistant atopic dermatitis. However, 2 months after starting, the patient begins to develop severe eye pain and decreased vision. Fortunately, he knows someone who is an ophthalmologist in the area. She tells him that the medication he prescribed is causing cicatrizing conjunctivitis and keratitis in his patient, and also to pick up Chili's on the way home from work. What medication did he prescribe?
BONUS (+300): What two interleukins does it affect?
Dupilumab
BONUS: IL-4 and IL-13
Patient has an upper respiratory infection and then develops multifocal infiltrates suggestive of IK. Syphilis and other infectious testing is negative. You tell her this three times because she keeps asking you to repeat. ESR is elevated. What treatment should you begin?
BONUS: What rheumatologic disease is this related to?
Systemic corticosteroids
BONUS: Polyarteritis nodosa
What is cenegermin and what is it used for?
Recombinant human nerve growth factor; neurotrophic keratopathy
Name all serotypes of adenovirus that lead to EKC. Must get all.
BONUS (+400): What serotypes cause pharyngoconjunctival fever?
8, 19,37, subgroup D
BONUS: 3, 7
What bacteria causes trachoma AND name 2 eponyms for clinical findings in trachoma.
Chlamydia; Arlt line, Herbert pits
Name all Foster stages for MMP
BONUS (+400): It's not MMP, and patient uses eyedrops. Name 2 of 3 mentioned in BCSC book
1. chronic conjunctivitis with subepithelial fibrosis
2. Fornix foreshortening
3. Symblepharon formation
4. Ankyloblepharon, frozen globe
BONUS: pilo, timolol, epinephrine
A patient with RA presents with eye pain and a peripheral crescentic epithelial defect. What is the procedural treatment that can be used for this disease, and why does it work?
BONUS: West Africans with Mooren ulcer should be worked up/treated for what infection? Not hep C
Excision or recession of adjacent conjunctiva
Removes source of inflammatory mediators
BONUS: Parasitic/helminthic
List two specific treatments for Demodex blepharitis. +100 for all three
BONUS (+200): Infectious disease that causes interstitial keratitis and neurotrophic keratopathy which was common in Biblical times
Lotilaner, tea tree oil, ivermectin
BONUS: Leprosy
What viruses cause acute hemorrhagic conjunctivitis?
BONUS (+500): One of these viruses causes a systemic syndrome in addition. What is that syndrome akin to?
Enterovirus, Coxsackievirus A24
BONUS: Polio
Protazoal cause of infectious keratitis in immunocompromised individuals and treatment (cannot answer voriconazole or floxacins, I'm looking for a specific one)
BONUS (+500): What is the stain?
Microsporidiosis, fumagillin
BONUS: Brown and Hopps
A patient presents with "woody", yellowish fibrinous membranes on his conjunctiva. What is the disease and what is he deficient in?
BONUS (+800): IV Treatment for plasminogen deficiency type 1
Ligneous conjunctivitis, plasminogen
BONUS: Ryplazim
A patient presents with focal eye pain and redness that does not blanch with phenylephrine. She has known sarcoidosis which resulted in chronic anterior uveitis for which she developed severe secondary glaucoma that was recently treated with incisional glaucoma surgery with MMC and aggressive post-op steroids. What is the next step in management?
Scleral cultures and antibiotics
What gene mutation AND chromosome are implicated in the inherited disease that causes limbal stem cell failure and secondary glaucoma.
PAX6, 11p13