CTE

Stages

100

How many stages of CTE are there?

4

200

True or False: 

The brain gains weight during stage 4 

Fasle

The brain dramatically loses weight

300

In stage 1, tau protein is restricted to which part of the brain?

Frontal Cotex

400

What enlarges during stage 2 of CTE?

Ventricles 

500

What key regions of the brain get affected during stage 3?

Hippocamous & Amygdala

Symptoms

100

At what stage do you start to lose focus?

Stage 1

200

Stage 4 has more severe symptoms of what stage?

Stage 3

300

At what stage should you get seen for your symptoms by a doctor?

Stage 1 or 2 (preferably 1) 

400

Name 2 stage 1 symptoms of CTE

short-term memory loss, mild aggression, depression, headaches, and loss of focus

500

During stage 3, you experience executive dysfunction. What is executive dysfunction?

An inability to complete activities that require time management, organization, and problem-solving

Care

100

Is there a cure for CTE?

No 😭

200

How and when can you determine if CTE is present?

Only after death 💀 can you examine the brain tissue

300

What can you do to prevent further head trauma? 

Use helmets, allow adequate time for recovery, and strengthen neck muscles. 

400

What can you do to help manage CTE?

Medication for symptoms and cognitive physical therapy

500

What do you look for when examining the brain?

Bonus: How do you detect the accumulation of tau protein in the brain?

Brain weight, enlarged ventricles, septal abnormalities, and brainstem darkness

Special Stains

FUN =]

100

What is Goodale's first name?

Wrong, you shouldn't know that. +/-100 points

200

Is CTE bad?

Yes, 100%, 1000%, duh, obviously!

300

What gender is CTE most common in?

Bonus: Name the 3 leading sports in CTE? (300)

Males

Football, Hockey, Boxing

400

Name 4 complications of CTE?

Dementia, Depression, Suicidal Thoughts, ALS

500

What does ALS stand for?

Bonus: Name 3 symptoms of ALS

Amyotrophic Lateral Sclerosis

Motor neuron degeneration, muscle weakness, paralysis, and twitching. difficulty eating, breathing, and moving

CTE 101

100

What repeated traumatic head injury leads to CTE?

Concussion

200

What does CTE stand for?

Chronic Traumatic Encephalopathy

300

What protein is abnormally built up in the brain?

Tau protein

400

What is the tau protein's function when CTE is active in the brain? 

Disrupt neural communication and cause cell death

500

Tau protein moves along the brain's neural network. What specific areas do these target? 

Neurons and astrocytes