Basics
What does CF stand for?
Cystic Fibrosis
CF is inherited in what pattern?
Autosomal recessive
What is a common lung symptom of Cf?
Chronic cough with thick mucus, wheezing
What test is done on newborns to screen for CF?
A blood test shortly after birth
Do traditional treatments cure CF or manage symptoms?
Manage
What substance builds builds up in the lungs in CF?
Thick, sticky mucus
what do you call someone with one faulty CF gene?
Carrier
What is unusual about the sweat of someone with CF?
It is very salty
Are there more adults or children living with CF in the US?
Why do people with CF need a high-calorie diet?
To maintain weight and energy
CF mainly affects which organ system?
The lungs (respiratory system)
How many faulty genes are needed to have CF?
Two
Why do people with CF have trouble gaining weight?
They can't properly absorb nutrients
What is the main test used to confirm CF?
The sweat test
What type of therapy helps remove mucus from the lungs?
Airway clearance
CF is caused by a problem with what type of protein?
CFTR protein
If both parents are carriers, what is the chance a child has CF?
25%
How can CF affect bones?
Can lead to low bone density --> higher risk of fractures
What does the sweat test measure to diagnose cystic fibrosis?
Salt (chloride) levels
What makes CFTR modulators different from traditional treatments?
They target the root cause of the disease
Why does mucus become thick and sticky in cystic fibrosis?
Because the CFTR protein doesn't move salt and water properly
Why can two healthy parents have a child with cystic fibrosis?
Because they are both carriers of the CF gene
Why does cystic fibrosis affect digestion?
Thick mucus blocks the pancreas, preventing enzymes from reaching the intestines
What type of testing is used to confirm cystic fibrosis by identifying CFTR mutations?
Genetic testing
Why are daily treatments important for people with cystic fibrosis?
To prevent mucus buildup and reduce infections