Methods
This is the cell type used in the paper
What are primary human macrophages?
This agent will depolymerize microtubules
What is nacodazole?
The movement where the probability of taking n consecutive steps in one direction is 2^n
What is 1D Random Walk?
These filaments were co-localized with linear motility
What are micro-tubules?
The cell used to study the clustering and transport of CD36
What are macrophages?
This fluorescent agent was used to image receptors colocalized with microtubules
What are quantum dots?
This is the fluorophore used in the paper
What is Cy3?
This algorithm used to be the gold standard for receptor tracking.
What is Multiple Hypothesis Testing?
This motility has the highest fluorescent intensity
What is linear motility?
The ligand which binds with CD36
What is oxidized LDL?
This technique was used to determine that most receptors were surface bound
What is acid wash?
This agent inhibits polymerization of actin filaments?
What is Latrunculin?
This mathematical technique is used to differentiate unconfined from confined diffusion.
What is Moment Scaling Spectrum?
This motility has the highest probability of the three investigated in the paper
What is isotropic confined motility?
The three cell types that express the CD36 receptor
What are platelets, macrophages, and endothelial cells?
This is the minimum duration of fusion required to form a cluster
What is one second?
This agent is an inhibitor mostly specific for Myosin II
What is blebbistatin?
This mathematical technique was used determine if receptors were genuinely forming clusters.
What is cross correlation?
This motility favours metastable clustering over all others
What is linear motility?
This is the polymer form of actin
What is F-actin?
This is the optimal dilution ratio of the secondary Cy3 antibody used to label CD36
What is 1:3000?
This subunit of cholera toxin was used to assess the prevalence of lipid raft transport
What is B?
This is the mathematical technique used to determine if receptors were genuinely forming clusters
What is cross-correlation?
The scaling coefficient of unconfined diffusion
What is greater than one?
CD36 receptors are involved in the detection of this infected cell type
What are malaria infected erythrocytes?