Focus Frenzy
In ADHD, these neurotransmitters are increased by stimulant medications and help explain their therapeutic effect.
What are dopamine and norepinephrine?
This medication is often used as a short-term alternative to benzodiazepines for anxiety, but its anticholinergic and sedating effects limit long-term use.
What is hydroxyzine?
These symptoms of schizophrenia include flat affect, alogia, avolition, and anhedonia.
What are negative symptoms?
This symptom must be present for the diagnosis of major depressive disorder: either depressed mood or this loss of interest or pleasure.
What is anhedonia?
This melatonin receptor agonist for insomnia should not be taken with or immediately after a high-fat meal because food can delay its absorption.
What is ramelteon?
According to DSM-5 criteria for ADHD, symptoms must be present in at least this many settings.
What are 2 or more settings?
This brand name anxiety medication has no potential for abuse, tolerance, or physiological dependence and may be favored when benzodiazepine misuse is a concern.
What is buspirone?
This major advantage explains why second-generation antipsychotics are generally preferred over first-generation antipsychotics in schizophrenia.
What is a lower incidence of extrapyramidal symptoms (EPS)?
This tertiary amine TCA is known for being more sedating and having stronger anticholinergic effects than secondary amine TCAs.
What is amitriptyline?
This orexin receptor antagonist for insomnia should be avoided with strong CYP3A inhibitors and may require dose adjustments with moderate CYP3A inhibitors.
What is suvorexant?
This ADHD medication is a non-stimulant that can be considered when stimulant abuse or diversion is a concern and is also used for anxiety in some patients.
What is atomoxetine?
This transdermal methylphenidate product should be applied about 2 hours before the desired effect and any remaining patches should be discarded by flushing down the toilet.
What is Daytrana?
This antipsychotic used to require enrollment in a REMS program and ANC monitoring because of risk of agranulocytosis/neutropenia.
What is clozapine?
Patients taking MAOIs should avoid foods high in this substance because it can precipitate a hypertensive crisis.
What is tyramine?
This CYP enzyme is primarily responsible for buspirone metabolism, which is why strong inhibitors can substantially increase buspirone concentrations.
What is CYP3A4?
This brand name ADHD patch should be applied about 2 hours before the desired effect for school/daytime symptom control.
What is Daytrana?
This evening-dosed methylphenidate product is designed with delayed drug release so symptom control begins the next morning before school.
What is Jornay PM?
These brand-name long-acting injectable formulations of paliperidone are given monthly, every 3 months, and every 6 months.
What are Invega Sustenna, Invega Trinza, and Invega Hafyera?
This brand name antidepressant has dual activity as an SSRI and a 5-HT1A partial agonist, and unlike many other antidepressants, its absorption is significantly improved when taken with food.
What is Viibyrd?
This breast cancer medication, brand name Nolvadex, can have reduced effectiveness when taken with strong CYP2D6 inhibitors such as fluoxetine or paroxetine.
What is tamoxifen?
Stimulants should not be used within this many days of an MAOI because of risk of hypertensive crisis.
What is 14 days?
This combination product is FDA-approved for bipolar depression and pairs an atypical antipsychotic with an SSRI.
What is olanzapine/fluoxetine?
This brand name long-acting injectable olanzapine product requires a REMS program with monitoring for at least 3 hours after injection because of risk of severe sedation and delirium.
What is Zyprexa Relprevv?
This brand name intranasal NMDA receptor antagonist for treatment-resistant depression is only available through a restricted distribution system under a REMS program.
What is Spravato?
Before starting an MAOI after discontinuing fluoxetine, this long of a washout period is required because of fluoxetine’s long half-life and active metabolite.
What is 5 weeks?