Damage, recovery, plasticity
Formation of synaptic links between neurons
Synaptogenesis
Aids in process of synaptogenesis
Sleep
Myelination is produced by what?
Oligodendrocytes in CNS and Schwann cells in PNS
T/F: Neurons do not die on their own
True
Reorganization of synaptic networks
Neuroplasticity
Create pre/post synaptic channels
Synaptic assembly
Process of pruning away axonal connections that are not competitive, stimulated, used, or needed
Early childhood and again in adolescents (mid 20s)
Synaptic pruning
Surges first few years of life, middle childhood, and early adolescence
Neurons in the olfactory epithelium and hippocampus
T/F Axon death affects the cells connected to it as well
True
Differentiate channels for neurotransmitters
Synaptic formation
Programmed cell death
Apoptosis
What causes DAI?
Twisting and shearing of myelinated axons
Unplanned cell death, due to anoxia/hypoxia/trauma/poisoning
Necrosis
Immediate cell body death, direct result of insult/trauma/injury, liquefaction, resulting in degeneration of axons and synapses
Primary neuronal cell death
When does synaptogenesis begin?
Around 18 weeks gestation
Reason for apoptosis
Too many disconnected, unused cells floating around disrupts efficiency, connectivity, and speed, of the entire system
Auto-immune disease, deterioration of myelination in CNS, replaced with plaque, atrophy of CC
MS
What gets rid of dead cells
Macrophages
Occurs after the trauma/insult/injury,
Secondary neuronal cell death
Purpose of synaptogenesis
Mental flexibility, adaptation, new learning, memory
When will all nerve cells be developed?
By 25th week in utero
Auto-immune attack of myelin in the PNS, rapid onset,
Guillain barre
Necrosis vs Apoptosis
Necrosis: messy, unplanned cell death
Apoptosis: clean, programmed cell death
Death of cell body as result to damage to the axon
Primary or secondary necrosis
axonal (retrograde) degeneration