Innate & Adaptive Immunity
Hypersensitivity Reactions
Hematologic Disorders
Anemias
Genetics and cellular
100

A nurse assesses a patient with a small cut that is warm, red, and swollen. Which innate process is responsible?

  • A. Complement activation

  • B. Inflammatory response

  • C. Adaptive immunity

  • D. Humoral immunity

B. Inflammatory response

100

A nurse is assessing a patient who developed hives and wheezing minutes after eating shellfish. Which hypersensitivity type is occurring?

Type I IgE‑mediated

100

A nurse is caring for a neutropenic patient with a fever of 101.8°F. Which action is most important?

Initiate reverse isolation and notify provider

100

A nurse is assessing a pregnant patient with fatigue and pica. Which lab result supports iron‑deficiency anemia?

Microcytic, hypochromic RBCs

MCV and MCHC is low 

100

A nurse is assessing a patient whose leg appears smaller after 6 weeks in a cast. Which cellular adaptation occurred?

Atrophy

200

Which finding indicates complement activation during infection?

  • A. Decreased neutrophil activity

  • B. Enhanced phagocytosis and cell lysis

  • C. Suppressed inflammatory response

  • D. Increased B‑cell memory formation

B. Enhanced phagocytosis and cell lysis

200

A nurse is monitoring a patient who develops fever and back pain during a blood transfusion. Which mechanism explains this reaction?

D. IgG/IgM‑mediated RBC destruction

200

A nurse is assessing a teen with mononucleosis who reports left upper‑quadrant pain. Which complication is the nurse concerned about?

Splenic enlargement and risk of rupture

200

A nurse is assessing a patient with numbness and gait instability. Which deficiency causes these symptoms?

Vitamin B12 deficiency

200

A nurse is reviewing a diagnosis of benign prostatic hyperplasia. Which type of cellular adaptation is this?

Hormonal hyperplasia

300

A nurse is caring for a patient experiencing acute transplant rejection. Which immune component is primarily responsible?

  • A. B‑cell overactivation

  • B. IgE‑mediated response

  • C. Complement deficiency

  • D. Cytotoxic T‑cell attack on donor tissue

D. Cytotoxic T‑cell attack on donor tissue

300

A nurse is assessing a patient with lupus who reports joint pain and a facial rash. Which process is responsible?

Immune complex deposition causing inflammation

300

A nurse is reviewing biopsy results for a patient with suspected lymphoma. Which finding is specific to Hodgkin lymphoma?

Presence of Reed‑Sternberg cells

300

A nurse is reviewing labs for a patient with macrocytic anemia. Which finding differentiates folate deficiency from B12 deficiency?

Absence of neurological symptoms

300

A nurse is providing genetic counseling to a patient with Marfan syndrome. Which inheritance pattern applies?

50% chance

400

A nurse is reviewing the immune response after a patient receives a second vaccine dose. Which response is expected?

  • A. Slow antibody production

  • B. No immune response

  • C. Rapid antibody production from memory B cells

  • D. Increased neutrophil migration

C. Rapid antibody production from memory B cells


400

A nurse is evaluating a patient who developed redness and vesicles 48 hours after poison ivy exposure. Which mechanism is responsible?

Delayed T‑cell–mediated hypersensitivity

400

A nurse is reviewing labs for a patient with fatigue and frequent infections. Which result supports leukemia?

  • A. Elevated platelets

  • B. High mature neutrophils

  • C. Leukopenia with immature blast cells

  • D. Increased RBC count

Leukopenia with immature blast cells

400

A nurse is caring for a patient with petechiae and frequent infections. Which mechanism explains these symptoms?


Bone marrow failure causing pancytopenia

400

A nurse is reviewing newborn genetic results showing monosomy X. Which condition is expected?

Turner syndrome

500

A nurse is teaching a patient about interferons. Which statement demonstrates correct understanding?

  • A. “They kill infected cells directly.”

  • B. “They prevent viral replication in nearby uninfected cells.”

  • C. “They stimulate antibody production.”

  • D. “They activate complement proteins.”

B. “They prevent viral replication in nearby uninfected cells.”

500

A nurse is reviewing the chart of a patient who developed bronchospasm and hypotension after receiving IV penicillin. The provider documents “recurrent reactions with repeated exposure.” Which immunologic process is responsible?

Type I IgE‑mediated reaction

500

A nurse is assessing a patient with multiple myeloma who reports bone pain. Which additional finding is expected?

Hypercalcemia from bone destruction

500

A nurse is assessing a patient with suspected hemolytic anemia. The patient reports dark urine and jaundice. Which finding supports this diagnosis?

Elevated bilirubin levels

500

A nurse is reviewing genetic results for a child diagnosed with Fragile X syndrome. Which assessment finding is consistent with this disorder?

Long narrow face with large ears