Alcohol-induced liver disease
The enzyme used to metabolize low to moderate levels of alcohol
What is alcohol dehydrogenase?
Impaired liver function leads to the accumulation of this neurotoxin in hepatic encephalopathy
What is ammonia?
The most abundant CYP enzyme in the body
What is CYP3A4?
The initial stage of alcoholic liver disease, characterized by the accumulation of fat droplets within liver cells
What is hepatic steatosis?
Name of the clinics that offer primary care, behavioral health, and dental services to low-income and unhoused individuals in Austin (hint: rhymes with immunity)
What are CommUnityCare Health Centers?
Jaundice occurs during this stage of alcohol-induced liver disease
What is alcoholic hepatitis?
A deficiency in this vitamin causes Wernicke's encephalopathy; another name for thiamine
What is vitamin B1?
What CYP450 stands for (hint: there are three parts)
What is cytochrome, pigment, and 450 nm?
The stage of alcoholic liver disease in which regenerating nodules are formed; the final stage
What is cirrhosis?
This program in Austin provides mental health and substance use disorder services (hint: rhymes with podagral)
What is Austin Travis County Integral Care?
The main enzyme in the microsomal ethanol oxidizing system (MEOS) which becomes more prominent in chronic alcohol users
What is CYP2E1/cytochrome P450 2E1?
Without treatment, Wernicke's encephalopathy can lead to this memory disorder
What is Korsakoff syndrome?
Another organ in which CYP450 enzymes are expressed besides the liver
What is small intestine, lungs, kidneys, brain, uterus or placenta?
"Chicken wire" pattern of fibrosis surrounding individual hepatocytes
What is pericellular fibrosis?
One example of an organization that provide addiction services for unhoused individuals in Austin
What is Austin Recovery, Salvation Army Adult Rehabilitation Center, Caritas of Austin, Front Steps or Austin Travis County Integral Care?
Build-up of serous fluid in the peritoneal cavity as a result of cirrhosis and liver failure
What is ascites?
The classic triad of symptoms for Wernicke's encephalopathy
What is confusion, ataxia, and nystagmus/ophthalmoplegia?
The three types of Phase I reactions which are carried out by CYP450 enzymes
What are oxidation, reduction, and hydrolysis?
One example of a stain that is used to assess fibrosis
What is silver impregnation, chromotrope-aniline blue, Masson's trichrome, Sirius Red, Victoria Blue or orcein staining?
Full name of the insurance program that Central Health offers to low-income, uninsured or unhoused Travis County residents
What is Medical Access Program?
A model for evaluating the severity and prognosis of alcoholic hepatitis
What is Maddrey's discriminant function?
Decreased activity of this thiamine-dependent enzyme of the TCA cycle can lead to Wernicke's encephalopathy
What is alpha-ketoglutarate dehydrogenase complex?
High scores for these two score systems indicates decreased CYP3A activity and worsening liver function
What are Child-Pugh Score and MELD Score?
Eosinophilic cytoplasmic inclusions within swollen hepatocytes in alcoholic hepatitis
What are Mallory-Denk bodies?
Cost of an emergency room visit if you have the Central Health insurance program MAP
What is $25?