Acute
See Case 1. What is the most likely antibody to be seen?
BONUS: Is this antibody found on the "ganglioside" panel sent at UCM?
What is Gq1b?
BONUS: It's NOT. Send separately.
The time interval after which an acquired, inflammatory neuropathy is considered CIDP (and not AIDP)
What is 8 weeks?
Case 2. What is the antibody most likely found?
What is GM1?
If this is not checked and fixed, it can create false positive results of demyelination (slow conduction velocities)
What is cold temperature in extremities?
Artist who has won the most Grammy's for Album of the Year
The general benchmark of WBC in CSF that should prompt one to consider an alternative diagnosis than GBS
Clinical features that distinguish AIDP from CIDP include...
Respiratory involvement, autonomic involvement cranial nerve involvement
Case 3. What are the possible antibodies that could be found?
What are nodal or para-nodal antibodies?
Neurofascin, contactin, or CASPR
One of the earliest signs of demyelination that can be seen on NCS is..
Michael Phelps
A patient is diagnosed with GBS. What is the infection most linked with need for mechanical ventilation?
What is campylobacter
Objective and/or scales used to measure improvement (or relapse) in CIDP
INCAT
I-RODS
Jamar hand grip strength
Rydell vibration
Case 4. What is most likely to be found in serum?
What is anti-MAG?
The EFNS criteria for CIDP defines conduction block as this.
Greater than 30 percent drop in amplitude between proximal and distal site, 50% in median and ulnar nerves
The longest running animated TV show
What is The Simpsons
The highest cause of mortality/morbidity in patients with GBS come from...(2)
Cardiac arrythmia and respiratory failure
The most common mutation for INHERITED demyelinating neuropathy
PMP22 Duplication
Case 5. What additional serum testing would help confirm the diagnosis?
Direct Coombs test (direct antiglobulin test [DAT])
Looking for cold agglutinin
What is sural sparing pattern?
The book found and "inspired" the person who assassinated John Lennon
Catcher In The Rye
The mechanism of action for the most recently approved medication for treatment of CIDP
What is FcRN receptor antagonist (subcutaneous, efgartigimod)
Case 6.What is most likely found in serum?
What is elevated VEGF