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Symptoms and Treatment
Disease
100
What type of genome does dengue virus have?
(+)ssRNA
100
What are the typical treatment methods for DENV infection?
Treatment of symptoms (blood transfusion, electrolyte balance, pain management, sedatives)
100
True or False. The disease can be asymptomatic.
True
200
What type of protein product does the DENV genome code for?
a single polyprotein that is cleaved by autoproteases
200
Name one common symptom of dengue virus infection.
joint pain (arthalgia) rash, fever, thrombocytopenia
200
Give one nickname for Dengue Fever.
“bone break fever” or “bone crusher disease”
300
To which family does Dengue virus belong?
Flaviviridae
300
What vaccine type is currently being tested?
Tetravalent or live attenuated
300
What is the scientific name of the transmission vector for dengue virus?
Aedes aegypti
400
How many serotypes of Dengue virus are there?
4
400
What is the main symptom that distinguishes Dengue from Chikungunya?
shock (I know...it's shocking)
400
How do you acquire hemmorraghic fever?
re-infection with a different serotype
500
Antibodies primarily target which DENV proteins?
E and prM
500
What is the medical term for decreased platelets?
thrombocytopenia
500
What does “ADE” stand for?
Antibody dependent enhancement