CCUS: Canine Chronic Ulcerative Stomatitis
This outdated term for CCUS referred to the area around the tooth.
What is CUPS or Canine Ulcerative Paradental Stomatitis?1
Name three differentials for CCUS.
What are Pemphigus vulgaris, Bullous Pemphigoid, Erythema Multiforme, Lupus Erythematosus, Epitheliotropic T-cell lymphoma, Uremic stomatitis?
This breed of dog is considered the "poster child" for eosinophilic stomatitis.
What is a Cavalier King Charles Spaniel?
Pentoxifylline decreases the production of these by phagocytes.
What are inflammatory cytokines?
What is the recommended frequency for dental cleanings in dogs with CCUS?
What is every 3-9 months?
What percentage of lesions occur in edentulous areas?
What is 40%?
This uncommon inflammatory skin disease can affect the skin, mucosa, and mucocutaneous junctions, and 30% of cases involve the oral cavity.
What is erythema multiforme?
Name two potential triggers for the hypersensitivity reaction that causes eosinophilic stomatitis.
What are environmental allergens, ingested materials (food, dander), parasitic infections (ectoparasites)?
Doxycycline inhibits these, which break down periodontal tissue.
What are matrix metalloproteinases?
Name one type of oral antiseptic that can be used to help break down the plaque biofilm.
What is 0.12% Chlorhexidine Zinc Oral Rinse?
Name two clinical signs that an owner might notice in a dog with CCUS.
What are fetid breath, ropey saliva, oral ulcers, weight loss, irritability, depression, lethargy?
What type of testing may be required to differentiate erythema multiforme from epitheliotropic T-cell lymphoma?
What is clonality testing?
Where is the most common location for an eosinophilic granuloma?
What is the palate?
Niacinamide is also known as this vitamin.
What is vitamin B3?
Name two examples of diligent home care that can be recommended for dogs with CCUS.
What are daily brushing of teeth, antiplaque water additive?
Contact mucositis, also called a "kissing lesion," is suspected to be what kind of response to dental plaque?
What is an inappropriate response?
Epitheliotropic T-cell lymphoma makes up what percentage of oral neoplasms?
What is 5%?
What percentage of asymptomatic dogs with eosinophilic stomatitis resolve without medications?
What is 70%?
Cyclosporine is an immunosuppressant that inhibits the function of these cells.
What are T cells?
This type of extraction involves the removal of specific teeth that are likely to have opposing ulcerative plaques.
What is a partial mouth extraction or strategic extraction?
Besides the buccal mucosa, name three other areas in the mouth where lesions might appear.
What are the lateral margins of the tongue, mucocutaneous junctions of the lip, edentulous areas, glossopalatine folds, palate?
This autoimmune disease of the skin can affect the nose, planum, nares, and lips, but rarely the oral cavity.
What is Discoid Lupus Erythematous?
Name two medications that are commonly used to treat symptomatic eosinophilic stomatitis.
What are prednisone and budesonide?
When used in conjunction with cyclosporine, metronidazole is speculated to suppress this enzyme, leading to increased plasma concentration of cyclosporine.
What is the CYP3A4 enzyme?
What is an important consideration for both partial and full mouth extractions, especially in large breed dogs?
What is staging the procedure?