Show:
A is for Acronyms, M is for Mnemonics
I guess I am also a pharmacist now?
Surgical Uh-Ohs
100

What is the finding which the mnemonic "HAAPPIED" is used for?

Eosinophilic spongiosis

100

What does Bimzelx inhibit? (Be as specific as possible)

IL-17 A and F

100

Name 2 early signs of lidocaine toxicity

Perioral numbness

Metallic taste

Tinnitus

200

List the history findings in PLEVA

P: Parakeratosis
L: Lichenoid infiltrate
E: Extravasation of erythrocytes
V: V-shaped dermal lymphocytic infiltrate
A: Acute epidermal changes

200

What does vismodegib inhibit?

Smoothened

Target sonic hedgehog pathway by inhibiting smoothened → SUFU stays bound to GLI → GLI1/2 transcription factors stay inactive → inhibition of transcription of target genes.

200

Which is permanent? Motor or sensory nerve damage?

Motor

300

What is the mnemonic for ddx with a Grenz Zone? 

 G-CALL

  • Granuloma faciale
  • Colloid milium
  • Acrodermatitis chronica atrophicans
  • Lepromatous leprosy
  • Leukemia/lymphoma cutis
300

What specific ocular finding is most common AE of dupilumab?

Conjunctivitis > Keratitis

300

Locate the 3 danger zones

1. Superficial temporary nerve - will knock out brow lift ability -> ptosis 

2. Marginal mandibular nerve - will knock out the depressors so the mouth cannot fall 

3. Spinal accessory nerve - winged scapula

400

What is the ddx for painful tumors?

BLEND AN EGG or BANGLES

  • Blue rubber bleb nevus
  • Leiomyoma
  • Eccrine spiradenoma
  • Neuroma
  • Dermatofibroma


  • Angiolipoma
  • Neurilemmoma (Schwannoma)


  • Endometrioma
  • Glomus tumor
  • Granular cell tumor
400

Which of the following increases risk of SCC/KA?

A. Trametinib

B. Vemurafenib

C. Ipilimumab

D. Nivolumab

B - BRAF inhibitors increase SCC risk. Adding a MEK inhibitor reduces the risk!

400

If you have DFSP with fibrosarcomatous change, what screening tools do you use and why?

CT Chest imaging, high risk of mets to the lungs.

500

What does LEOPARD stand for?

L - lentigines, E - EKG abnormalities, O - ocular hypertelorism, P - pulmonary stenosis, A - abnormal genitalia, R - retardation of growth, D - deafness

500

What is the drug name / mechanism of the immunotherapy used for Merkel Cell?

Avelumab (PD-L1) or Pembro (PD-1) inhibitors

  • PD-1 on activated T cells binds to its ligands PD1-L1 (B7-H1) and PD1-L2 (B7-DC), which are expressed on tumor cells → deactivation of T cells → loss of immune response against tumor
500

A patient is getting Mohs for a SCC on the lip. The defect spans the lower ⅔ of the lip and the plan for recon is an Abbe flap. His history includes allergy to penicillin, knee replacement 6 months ago, and a pacemaker. Do you give antibiotics? If so, what do you give?

Yes, you are breaching oral mucosa with this flap. He is at risk for joint infection. He is allergic to penicillin so you give either: 

Clinda, Azith, or Clarithro