Clinical manifestations, affected body systems
Type I
o Insulin cells are destroyed
o Glucose in bloodstream, glucose in urine, ketone bodies increase
Type II
o Beta cells can’t keep up with insulin demand
o Onset is progressive: mild symptoms initially
Diet
50-60% carbs
20-30% protein
10-20% fats
1 unit of insulin= 15g carbs
Must distribute calories amongst meals: carb budget of 45-60g per meal
Exchange list
o Bread, veggies, milk, fruit, fats
o Can pick and choose from categories
Survival skills
Pathophysiology
Treatment modalities
Recognition, treatment, and prevention of hypo/hyperglycemia
Pragmatic info: where to buy and storer insulin, when to contact PCP
Hypoglycemia: clinical manifestations; treatment at home and in hospital
Clinical manifestations
o Shaky
o Tachycardia
o Sweaty
o Dizzy
o Anxious
o Hungry
o Weak
o Blurred vision
Treatment
o Treat with concentrated carbs
o Always carry a fast-acting form of sugar
Alcohol
Should drink alcohol with a meal or immediately before to help prevent
alcohol induced hypoglycemia
Wear a medical alert bracelet
Sick day rules
Stick to same medication routine
Increase testing for glucose and urine ketones every 3-4hours
Drink fluids with sugar every 30-60min for calories and to prevent dehydration
If unable to retain fluids seek medical attention
DKA
Lack of insulin causes increased fat breakdown which increases ketone bodies making the blood more acidic
Causes:
o Sepsis
o Sickness
o Stress
o Skip insulin
Clinical manifestations
o Rapid onset: less than 24 hours
o Early s/s: frequent urination, thirst or dry mouth, high blood glucose, high ketones
o Late s/s: tired, n/v, dry skin, fruity breath, hard time breathing, confusion
o Blood glucose: 200-500+
Treatment
o Rehydration
Start with normal saline
When under 300 bg change to D5W (want to bring
down sugar slowly)
o Hourly blood glucose checks
Insulin
Rapid (used for DKA)
Short: used before meals
Intermediate: used at nighttime
Short and intermediate are usually used together
HHS
Persistent hyperglycemia causes loss of water and electrolytes
Clinical manifestations
o Slower onset of several days to weeks
o Signs of dehydration and neurological issues
Assessment
o Blood glucose 600-1200
Treatment
o Monitor volume and electrolytes
o Replace fluid loss slowly
o Insulin replacement therapy
o Correct underlying cause
o Prevent complications
Fluid overload, pulmonary edema, heart failure,
hypokalemia, hypoglycemia, cerebral edema