Glipizide
Contraindications for Glipizides (3 things)
What is: dont take this if you're pregnant, dont take this with alcohol, beta blockers can ask the shikiness effects in hypoglycemia
Contraindications of Repaglimides (3 things)
what is: patients should not take with sulfonylureas because they are so similar, do not take with alchol, dont give to patients with liver damage
Biggest effect of Pioglitazone (TZD)
What is: Fluid Retention
MOA of Metformin (3 things)
What is: decreases glucose production, inhibits glucose production, increases insulin sensitivity
Effects of Acarbose:
What is: frequent GI distress (bloating, cramping, diarrhea, borborygmus), decreased iron absorption, liver dysfunction
MOA of Glipizides
What is: Stimulates insulin secretion (pancreas), increases insulin sensitivity in the tissues
MOA of Repaglinides
What is: Stimulates insulin secreation, increases insulin secretions
MOA of Pioglitazone (TZD)
What is: Increases insulin sensitivity, inhibits glucose production
Administration of Metformin
What is: with meals, 1-2 times a day
MOA of Acarbose
What is: delays carb absorption, decreased glucose absorption
What is the big effect of taking Glipizides (one thing)
What is: Hypoglycemia
Effect of Repaglinide:
What is: hypoglycemia
Patient education of Pioglipizide (TZD)
What is: fatigue, rapid weight gain, inability to lie down, monitor for AST/ALT, potentional to induce ovulation, fractures in women so do weight bearing exercise and take calcium and vitamin D supplements
Effects of Metformin (3 things)
What is: GI effects (intimacy), B12 deficiency, lactic acidosis toxicity
Patient education of acarbose
What is: monitor liver function, watch for bloating, gas, borpogymus, diarrhea, monitor for diarrhea
Administation of Glipizides
What is: take prior to meals 1-2 times daily
Administration of Repaglimides
What is: take prior to meals 1-2 times daily
Administration of Pioglitazones (TZD) & T1/2
What is: 1 times a day & 16-24 hrs
Contraindications of Metformin
What is: drinking alcohol, patients with low GFR
Effects of acarbose
What is: apples bananas, soda, hypoglycemia when given with insulin or sulfonylurea
Patient Education of Glipizides (d/t masked hypoglycemia)
What is: Due to the beta blocker masking the hypoglycemia: Sweating, shakiness, HA, severe vomitting
Contraindications of Pioglitazone (TZD)
What is: patients with HF, rifampin (CYP inhibitor), gemfibrozil (CYP inducer)
Patient education of Metformin
What is: take with food, monitor GFR, watch for numbness and tingling d/t B12 deficiency
Administration of Acarbose