One or more chambers of the heart are enlarged with thin heart muscle walls
What is Dilated Cardiomyopathy
The real culprits behind the neurohormonal response to reduced LVEF
What is the sympthetic nervous system response and renin angiotensin aldosterone sytem response
First line acute treatment for anyone in the cold & whatever category of acute decompensated heart failure
What are inotropes
Common vavular dysfunction as a result of the evolution of dilated cardiomyopathy
Stops the RASS from RASSin by blocking its catalyst
Angiotensin Converting Enzyme Inhibitor (ACE inhibitors)
Excess fluid builds up resulting in pulmonary edema as a result of this particular compensetory mechanism
What is the Frank-Starling Mechanism
Causes vasoconstriction, increased heart rate, sodium and water retention
What is Angiotensin II
Decreases venous preload and venous congestion
What is nitroglycerin
The reason DCM patients have to be on chronic anticoagulation
What is embolic stroke risk
Heads off the first of the deadly duo of neurohormonal culprits
Beta Blockers
This can be heard as a result of fluid overload when auscultating heart sounds
What is an S3 heart tone
Chronically elevated levels lead to myocardial remodeling and fibrosis
What is Angiotensin II or Aldosterone
Most common triple combination therapy for initial presentation of acute decompensated systolic heart failure
What are diuretics, nitroglycerin, and BiPAP
Helps the ventricles beat in sync to improve stroke volume
What is Cardiac Resynchronization Therapy (CRT)
Made its name off of putting an injuntion on neprilysin
What is ARNi (Entresto)
What is Mechanical Circulatory Support (MCS)
Kidneys excrete it as a result of sensed decreased renal perfusion to start the cascade
What is Renin
Contraindicated in hypotensive, cold/wet, acute systolic heart failure patients
What is a fluid bolus
40% of of deaths in DCM pts occur because of this
What is VT/VF
Blocks the mass exodus of electrolytes and also blocks a back door sneaky vasoconstrictor
What is MRA (Aldosterone antagonist)
The result of volume overload, diastolic wall stress, and ventricular remodeling.
What is eccentric hypertrophy
Common toxin which if discontinued may reverse the damage resulting in DCM
Chronic Alcohol Ingestion
May not always be the best intervention in cold & whatever categoried DCM patients in a tachycardic atrial arryhthmia
What is cardioversion
Most common electrical conduction abnormality in DCM
What is a bundle branch block
A magical sugar excreter but could give you gangrene in the junk
What are SGLT2 Inhibitors (gliflozins)